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Gene amiE from Pseudomonas aeruginosa PAO1: acylamide amidohydrolase
Member of NCBI Protein Clusters PRK13286(See COMBREX Page ) (See NCBI page)
NCBI Entrez GeneID 877816
UniProtKB accession
RefSeq Protein accession NP_252056.1 (PROVISIONAL)
Gene Symbol(s)
  • symbol: amiE
  • locus tag: PA3366
Organism Pseudomonas aeruginosa PAO1 (NCBI TaxID: 208964)
Other Cross References:
  • S
    Structure(s) available in PDB: 1K17 2UXY
  • C
    Gene cloned by a participant in the Protein Structure Initiative (PSI): TargetDB. (To obtain a clone, please contact the PSI:Biology-Materials Repository.)
  • U
    Protein purified by a participant in the Protein Structure Initiative (PSI): TargetDB. (If you are interested in collaborating to obtain the protein, please contact the Northeast Structural Genomics consortium).
  • Protein described in EcoCyc:
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Source Predicted function(s)
NCBI Protein Cluster Prediction acylamide amidohydrolase
Prof. Vitkup / Confidence:0.77 (References: 19935659, 16507154)
Source References Functional description
[PMID: 3108029]
[PMID: 10359655]
[PMID: 11955282]
Aliphatic amidase (source organism: Pseudomonas aeruginosa.; strain specific ID: PAC142)
Functional Status greenGreen (experimental evidence, uncurated)
EC number (See reaction via BRENDA)) (Source: BRENDA)
GO terms
  • BP: GO:0006807 : nitrogen compound metabolic process : IEA
  • MF: GO:0016810 : hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds : IEA
  • MF: GO:0004040 : amidase activity : IEA
  • MF: GO:0016787 : hydrolase activity : IEA
Domain Structure from CDD
  • COG0388: Predicted amidohydrolase [General function prediction only]
  • aliphatic_amidase: aliphatic amidases (class 2 nitrilases). Aliphatic amidases catalyze the hydrolysis of short-chain aliphatic amides to f.... (More)

See domain structure on NCBI Conserved Domain Database
Domain structure from Pfam
See domain structure on Pfam Database
Based on the function of this gene, COMBREX predictions were made to the following related genes (mouse over gene symbol for details) [Download ]
amiE (8) , PFLU2536