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Gene TM0542 from Thermotoga maritima MSB8: malate oxidoreductase
Member of NCBI Protein Clusters CLSK875209(See COMBREX Page ) (See NCBI page)
NCBI Entrez GeneID 897596
UniProtKB accession
RefSeq Protein accession NP_228352.1 (PROVISIONAL)
Gene Symbol(s)
  • symbol: TM0542
  • locus tag: TM0542
Organism Thermotoga maritima MSB8 (NCBI TaxID: 243274)
Other Cross References:
  • S
    Structure(s) available in PDB: 1VL6 2HAE
  • C
    Gene cloned by a participant in the Protein Structure Initiative (PSI): TargetDB. (To obtain a clone, please contact the PSI:Biology-Materials Repository.)
  • U
    Protein purified by a participant in the Protein Structure Initiative (PSI): TargetDB. (If you are interested in collaborating to obtain the protein, please contact the Northeast Structural Genomics consortium).
  • Protein described in EcoCyc:
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Source Predicted function(s)
NCBI Protein Cluster Prediction malate dehydrogenase
Source References Functional description
COMBREX Under Review Malate dehydrogenase / COMBREX-validated
Functional Status greenGreen (experimental evidence, uncurated)
GO terms
  • BP: GO:0055114 : oxidation reduction : IEA
  • MF: GO:0046872 : metal ion binding : IEA
  • MF: GO:0003824 : catalytic activity : IEA
  • MF: GO:0051287 : NAD or NADH binding : IEA
  • MF: GO:0016616 : oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor : IEA
  • BP: GO:0008152 : metabolic process : IEA
  • MF: GO:0005488 : binding : IEA
  • MF: GO:0016491 : oxidoreductase activity : IEA
Domain Structure from CDD
  • malic: Malic enzyme, N-terminal domain.
  • NAD_bind_2_malic_enz: NAD(P) binding domain of malic enzyme (ME), subgroup 2. Malic enzyme (ME), a member of the amino acid dehydrogenase (DH).... (More)

See domain structure on NCBI Conserved Domain Database
Domain structure from Pfam
See domain structure on Pfam Database