Gene nusB from Helicobacter pylori 26695: transcription antitermination protein NusB
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Member of NCBI Protein Clusters
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PRK00202(See COMBREX Page ) (See NCBI page)
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NCBI Entrez GeneID
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898756
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UniProtKB accession
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RefSeq Protein accession
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NP_206803.1 (PROVISIONAL)
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Gene Symbol(s)
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- symbol: nusB
- locus tag: HP0001
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Organism
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Helicobacter pylori 26695 (NCBI TaxID: 85962)
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Other Cross References:
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S Structure(s) available in PDB:
C Gene cloned by a participant in the Protein Structure Initiative (PSI):
TargetDB. (To obtain a clone, please contact the PSI:Biology-Materials Repository.)
U Protein purified by a participant in the Protein Structure Initiative (PSI):
TargetDB. (If you are interested in collaborating to obtain the protein, please contact the Northeast Structural Genomics consortium).
- Protein described in EcoCyc:
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Initiate the grant application process for experimentally validating this gene (Important notice about COMBREX grants.)
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Contribute a predicted function for this gene (free text, GO terms, or EC number) (info). Be sure to
check the list of current predicted functions in the section immediately below beforehand.
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Nominate this gene for the Gold Standard Gene Database (if you believe it has been experimentally
validated) (info).
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Post a comment about this gene to appear on this page (info).
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Functional Status
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blue (function predicted, no experimental evidence)
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Source of prediction
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NCBI Protein Clusters info
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BLASTP hits to experimentally validated proteins
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other hits with E-value < 1e-05
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Share the same Pfam domain composition with the following experimentally validated proteins
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to see the rest 3 genes click here
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GO terms
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BP:
GO:0006353 : transcription termination : IEA
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MF:
GO:0003723 : RNA binding : IEA
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BP:
GO:0006350 : transcription : IEA
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MF:
GO:0003715 : transcription termination factor activity : IEA
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BP:
GO:0045449 : regulation of transcription : IEA
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BP:
GO:0006355 : regulation of transcription, DNA-dependent : IEA
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Domain Structure from CDD
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- Terminator_NusB: Transcription termination factor NusB (N protein-Utilization Substance B). NusB plays a key role in the regulation of ribosomal RNA biosynthesis in eubacteria by modulating the efficiency of transcriptional antitermination. NusB along with other Nus factors (NusA, NusE/S10 and NusG) forms the core complex with the boxA element of the nut site of the rRNA operons. These interactions help RNA polymerase to counteract polarity during transcription of rRNA operons and allow stable antitermination. The transcription antitermination system can be appropriated by some bacteriophages such as lambda, which use the system to switch between the lysogenic and lytic modes of phage propagation..... (More)
See domain structure on NCBI Conserved Domain Database
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Domain structure from Pfam
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See domain structure on Pfam Database
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The table at right lists genes that may be "functionally linked to" (i.e., participate in a common biological process, or form a protein complex with) the subject gene of this page,
as determined by two sequence-independent methods, including phylogenetic profiling and operon membership (determined by OperonDB).
(Info.)
These linkages may also be viewed graphically using the program VisANT, by clicking on the headers of the table.
Note: VisANT requires Java. To install the latest version of Java, see www.java.com
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| | ribH | 6,7-dimethyl-8-ribityllumazine synthase | | | | | HP0003 | 2-dehydro-3-deoxyphosphooctonate aldolase | | | | | HP1590 | hypothetical protein | | | | | rplT | 50S ribosomal protein L20 | | | | | HP1362 | replicative DNA helicase | | | | | dnaE | DNA polymerase III subunit alpha | | | | | rpmI | 50S ribosomal protein L35 | | | | | HP1247 | DNA polymerase III subunit delta | | | | | ligA | NAD-dependent DNA ligase LigA | | | | | HP1448 | ribonuclease P, protein component (rnpA) | | | | | rplI | 50S ribosomal protein L9 | | | | | rplU | 50S ribosomal protein L21 | | | | | HP1051 | hypothetical protein | | | | | ruvA | Holliday junction DNA helicase RuvA | | | | | tig | trigger factor | | | | | mraW | S-adenosyl-methyltransferase MraW | | | | | HP0717 | DNA polymerase III subunits gamma and tau | | | | | HP0955 | prolipoprotein diacylglyceryl transferase | | | | | rbfA | ribosome-binding factor A | | | | | infC | translation initiation factor IF-3 | | | | | rpsT | 30S ribosomal protein S20 | | | | | tsf | elongation factor Ts | | | | | ruvB | Holliday junction DNA helicase RuvB | | | | | rpmE | 50S ribosomal protein L31 | | | | | HP0088 | RNA polymerase sigma factor RpoD | | | | | def | peptide deformylase | | | | | smpB | SsrA-binding protein | | | | | dnaA | chromosomal replication initiation protein | | | | | lspA | lipoprotein signal peptidase | | | | | trmD | tRNA (guanine-N(1)-)-methyltransferase | | | | | secE | preprotein translocase membrane subunit | | | | | secA | preprotein translocase subunit SecA | | | |
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