Combrex Enter Keyword, gene symbol, or identifier (more options; Help )
Enter species name
Gene functional status (select)
Phenotype association (select)[View list of phenotypes]
Check to restrict search to:
Genes in Category A-C and Emerging/Re-Emerging pathogens
Genes in curated Protein Clusters
Genes with predictions submitted to COMBREX
P
Genes with solved structures in PDB
S
Genes with Pfam domains shared with human proteins
H
Genes with products purified by PSI
U
Genes cloned by PSI
C
close options

 

Gene HP0250 from Helicobacter pylori 26695: oligopeptide ABC transporter, ATP-binding protein (oppD)
Member of NCBI Protein Clusters CLSK477327(See COMBREX Page ) (See NCBI page)
NCBI Entrez GeneID 898761
UniProtKB accession
RefSeq Protein accession NP_207048.1 (PROVISIONAL)
Gene Symbol(s)
  • symbol: HP0250
  • locus tag: HP0250
Organism Helicobacter pylori 26695 (NCBI TaxID: 85962)
Initiate the grant application process for experimentally validating this gene (Important notice about COMBREX grants.)
Contribute a predicted function for this gene (free text, GO terms, or EC number) (info). Be sure to check the list of current predicted functions in the section immediately below beforehand.
Nominate this gene for the Gold Standard Gene Database (if you believe it has been experimentally validated) (info).
Post a comment about this gene to appear on this page (info).
Source Predicted function(s)
NCBI Protein Cluster Prediction oligopeptide permease ATPase protein
Prof. David Horn 3.6.3: acting on acid anhydrides, catalyzing transmembrane movement / (References: 20034383)
Prof. Vitkup 3.6.3.24 / Confidence:0.039 (References: 19935659, 16507154)
Functional Status blueblue (function predicted, no experimental evidence)
Source of prediction NCBI Protein Clusters info
BLASTP hits to experimentally validated proteins
green yejF from Escherichia coli str. K-12 substr. MG1655
(%_identity=40.95; E_val=1e-110; BitScore=395.0)

other hits with E-value < 1e-05
Share the same Pfam domain composition with the following experimentally validated proteins
green oppD from Bacillus subtilis subsp. subtilis str. 168

to see the rest 10 genes click here
GO terms
  • MF: GO:0016887 : ATPase activity : IEA
  • MF: GO:0000166 : nucleotide binding : IEA
  • MF: GO:0005524 : ATP binding : IEA
  • BP: GO:0015833 : peptide transport : IEA
  • MF: GO:0017111 : nucleoside-triphosphatase activity : IEA
  • BP: GO:0006810 : transport : IEA
Domain Structure from CDD
  • COG1123: ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]
  • ABC_NikE_OppD_transporters: The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The N.... (More)
  • oligo_HPY: Oligopeptide/dipeptide transporter, C-terminal region. This model represents a domain found in the C-terminal regions of.... (More)

See domain structure on NCBI Conserved Domain Database
Domain structure from Pfam
See domain structure on Pfam Database
The table at right lists genes that may be "functionally linked to" (i.e., participate in a common biological process, or form a protein complex with) the subject gene of this page, as determined by two sequence-independent methods, including phylogenetic profiling and operon membership (determined by OperonDB). (Info.) These linkages may also be viewed graphically using the program VisANT, by clicking on the headers of the table. Note: VisANT requires Java. To install the latest version of Java, see www.java.com
 OperonDB
gene neighbourhoods
HP0251oligopeptide ABC transporter, permease protein (op