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Gene HP0772 from Helicobacter pylori 26695: N-acetylmuramoyl-L-alanine amidase (amiA)
Member of NCBI Protein Clusters CLSK496207(See COMBREX Page ) (See NCBI page)
NCBI Entrez GeneID 898764
UniProtKB accession
RefSeq Protein accession NP_207565.1 (PROVISIONAL)
Gene Symbol(s)
  • symbol: HP0772
  • locus tag: HP0772
Organism Helicobacter pylori 26695 (NCBI TaxID: 85962)
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Source Predicted function(s)
NCBI Protein Cluster Prediction N-acetylmuramoyl-L-alanine amidase
Prof. Vitkup / Confidence:0.221 (References: 19935659, 16507154)
Berkeley Phylogenomics Group GO:0008745 N-acetylmuramoyl-L-alanine amidase activity / (References: 19435885)
Functional Status blueblue (function predicted, no experimental evidence)
Source of prediction NCBI Protein Clusters info
BLASTP hits to experimentally validated proteins This gene does not have a BLAST match to any experimentally validated gene with an E value below 1e-5
Share the same Pfam domain composition with the following experimentally validated proteins
green amiB from Escherichia coli str. K-12 substr. MG1655

to see the rest 3 genes click here
GO terms
  • BP: GO:0009253 : peptidoglycan catabolic process : IEA
  • MF: GO:0008745 : N-acetylmuramoyl-L-alanine amidase activity : IEA
Domain Structure from CDD
  • MurNAc-LAA: N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Ami.... (More)

See domain structure on NCBI Conserved Domain Database
Domain structure from Pfam
See domain structure on Pfam Database
The table at right lists genes that may be "functionally linked to" (i.e., participate in a common biological process, or form a protein complex with) the subject gene of this page, as determined by two sequence-independent methods, including phylogenetic profiling and operon membership (determined by OperonDB). (Info.) These linkages may also be viewed graphically using the program VisANT, by clicking on the headers of the table. Note: VisANT requires Java. To install the latest version of Java, see
phylogenetic profile
HP0771hypothetical protein
HP0773hypothetical protein
HP0774tyrosyl-tRNA synthetase
ispG4-hydroxy-3-methylbut-2-en-1-yl diphosphate syntha 
HP03541-deoxy-D-xylulose-5-phosphate synthase 
HP02161-deoxy-D-xylulose 5-phosphate reductoisomerase 
HP14434-diphosphocytidyl-2-C-methyl-D-erythritol kinase 
ispH4-hydroxy-3-methylbut-2-enyl diphosphate reductase 
Metabolic Annotation from Palsson Lab

Metabolic Reaction: AMAA

N-acetylmuramoyl-L-alanine amidase
acmama[c] + h2o[c] -> acmam[c] + ala-DASH-L[c]
Peptidoglycan Biosynthesis

Source: Ported to COMBREX by Segre's Lab