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Gene HP1267 from Helicobacter pylori 26695: NADH dehydrogenase subunit H
Member of NCBI Protein Clusters PRK06076(See COMBREX Page ) (See NCBI page)
NCBI Entrez GeneID 898785
UniProtKB accession
RefSeq Protein accession NP_208059.1 (PROVISIONAL)
Gene Symbol(s)
  • symbol: HP1267
  • locus tag: HP1267
Organism Helicobacter pylori 26695 (NCBI TaxID: 85962)
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Source Predicted function(s)
NCBI Protein Cluster Prediction NADH dehydrogenase subunit H
Prof. Vitkup / Confidence:0.732 (References: 19935659, 16507154)
Berkeley Phylogenomics Group GO:0015453 oxidoreduction-driven active transmembrane transporter activity / (References: 19435885)
Functional Status blueblue (function predicted, no experimental evidence)
Source of prediction NCBI Protein Clusters info
EC number
BLASTP hits to experimentally validated proteins
green nuoH from Escherichia coli str. K-12 substr. MG1655
(%_identity=39.51; E_val=2e-59; BitScore=224.0)

other hits with E-value < 1e-05
GO terms
  • BP: GO:0055114 : oxidation reduction : IEA
  • CC: GO:0016020 : membrane : IEA
  • MF: GO:0050136 : NADH dehydrogenase (quinone) activity : IEA
  • CC: GO:0005886 : plasma membrane : IEA
  • CC: GO:0016021 : integral to membrane : IEA
  • MF: GO:0016491 : oxidoreductase activity : IEA
  • MF: GO:0048038 : quinone binding : IEA
Domain Structure from CDD
  • NADHdh: NADH dehydrogenase. NADH dehydrogenase subunit H; Provisional

See domain structure on NCBI Conserved Domain Database
Domain structure from Pfam
See domain structure on Pfam Database
The table at right lists genes that may be "functionally linked to" (i.e., participate in a common biological process, or form a protein complex with) the subject gene of this page, as determined by two sequence-independent methods, including phylogenetic profiling and operon membership (determined by OperonDB). (Info.) These linkages may also be viewed graphically using the program VisANT, by clicking on the headers of the table. Note: VisANT requires Java. To install the latest version of Java, see
gene neighbourhoods
phylogenetic profile
HP1265hypothetical protein
HP1266NADH dehydrogenase subunit G
HP1268NADH dehydrogenase subunit I
HP1269NADH dehydrogenase subunit J
HP1262NADH dehydrogenase subunit C  
HP1260NADH dehydrogenase subunit A  
HP1270NADH dehydrogenase subunit K  
HP1273NADH dehydrogenase subunit N  
HP1272NADH dehydrogenase subunit M  
HP1261NADH dehydrogenase subunit B  
HP1263NADH dehydrogenase subunit D  
Metabolic Annotation from Palsson Lab

Metabolic Reaction: NDH_1

NADH dehydrogenase (menaquinone) (complex I)
3 h[c] + mqn6[c] + nadph[c] -> 2 h[e] + mql6[c] + nadp[c]
Respiratory chain
Other Genes

Source: Ported to COMBREX by Segre's Lab