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Gene HP1293 from Helicobacter pylori 26695: DNA-directed RNA polymerase subunit alpha
Member of NCBI Protein Clusters PRK05182(See COMBREX Page ) (See NCBI page)
NCBI Entrez GeneID 898788
UniProtKB accession
RefSeq Protein accession NP_208085.1 (PROVISIONAL)
Gene Symbol(s)
  • symbol: HP1293
  • locus tag: HP1293
Organism Helicobacter pylori 26695 (NCBI TaxID: 85962)
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Source Predicted function(s)
NCBI Protein Cluster Prediction DNA-directed RNA polymerase subunit alpha
Functional Status blueblue (function predicted, no experimental evidence)
Source of prediction NCBI Protein Clusters info
EC number
BLASTP hits to experimentally validated proteins
green rpoA from Bacillus subtilis subsp. subtilis str. 168
(%_identity=34.01; E_val=6e-45; BitScore=176.0)

other hits with E-value < 1e-05
Share the same Pfam domain composition with the following experimentally validated proteins
green rpoA from Sinorhizobium meliloti 1021

to see the rest 10 genes click here
GO terms
  • MF: GO:0046983 : protein dimerization activity : IEA
  • BP: GO:0006351 : transcription, DNA-dependent : IEA
  • MF: GO:0003899 : DNA-directed RNA polymerase activity : IEA
  • BP: GO:0006350 : transcription : IEA
  • MF: GO:0016779 : nucleotidyltransferase activity : IEA
  • MF: GO:0016740 : transferase activity : IEA
  • MF: GO:0003677 : DNA binding : IEA
Domain Structure from CDD
  • rpoA: DNA-directed RNA polymerase, alpha subunit, bacterial and chloroplast-type. This family consists of the bacterial (and c.... (More)
  • RNA_pol_A_CTD: Bacterial RNA polymerase, alpha chain C terminal domain. hypothetical protein; Provisional
  • RNAP_alpha_NTD: N-terminal domain of the Alpha subunit of Bacterial RNA polymerase. The bacterial alpha subunit of RNA polymerase (RNAP).... (More)

See domain structure on NCBI Conserved Domain Database
Domain structure from Pfam
See domain structure on Pfam Database
The table at right lists genes that may be "functionally linked to" (i.e., participate in a common biological process, or form a protein complex with) the subject gene of this page, as determined by two sequence-independent methods, including phylogenetic profiling and operon membership (determined by OperonDB). (Info.) These linkages may also be viewed graphically using the program VisANT, by clicking on the headers of the table. Note: VisANT requires Java. To install the latest version of Java, see
gene neighbourhoods
rplQ50S ribosomal protein L17
HP129530S ribosomal protein S11
rpsD30S ribosomal protein S4