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Gene HP1206 from Helicobacter pylori 26695: multidrug resistance protein (hetA)
Member of NCBI Protein Clusters CLSK872522(See COMBREX Page ) (See NCBI page)
NCBI Entrez GeneID 898800
UniProtKB accession
RefSeq Protein accession NP_207998.1 (PROVISIONAL)
Gene Symbol(s)
  • symbol: HP1206
  • locus tag: HP1206
Organism Helicobacter pylori 26695 (NCBI TaxID: 85962)
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Contribute a predicted function for this gene (free text, GO terms, or EC number) (info). Be sure to check the list of current predicted functions in the section immediately below beforehand.
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Post a comment about this gene to appear on this page (info).
Source Predicted function(s)
NCBI Protein Cluster Prediction ABC transporter, ATP-binding/permease protein
Prof. Vitkup 3.6.3.43 / Confidence:0.108 (References: 19935659, 16507154)
Berkeley Phylogenomics Group GO:0008289 lipid binding / (References: 19435885)
Berkeley Phylogenomics Group GO:0005524 ATP binding / (References: 19435885)
Berkeley Phylogenomics Group GO:0042802 identical protein binding / (References: 19435885)
Berkeley Phylogenomics Group GO:0008144 drug binding / (References: 19435885)
Berkeley Phylogenomics Group GO:0042626 ATPase activity, coupled to transmembrane movement of substances / (References: 19435885)
Berkeley Phylogenomics Group GO:0005515 protein binding / (References: 19435885)
Berkeley Phylogenomics Group GO:0015238 drug transmembrane transporter activity / (References: 19435885)
Berkeley Phylogenomics Group GO:0015437 lipopolysaccharide-transporting ATPase activity / (References: 19435885)
Berkeley Phylogenomics Group GO:0043621 protein self-association / (References: 19435885)
Berkeley Phylogenomics Group GO:0034040 lipid-transporting ATPase activity / (References: 19435885)
Berkeley Phylogenomics Group GO:0005325 peroxisomal fatty acyl CoA transporter activity / (References: 19435885)
Functional Status blueblue (function predicted, no experimental evidence)
Source of prediction NCBI Protein Clusters info
BLASTP hits to experimentally validated proteins This gene does not have a BLAST match to any experimentally validated gene with an E value below 1e-5
Share the same Pfam domain composition with the following experimentally validated proteins
green ftsE from Bacillus subtilis subsp. subtilis str. 168

to see the rest 79 genes click here
GO terms
  • MF: GO:0016887 : ATPase activity : IEA
  • MF: GO:0000166 : nucleotide binding : IEA
  • MF: GO:0005524 : ATP binding : IEA
  • MF: GO:0042626 : ATPase activity, coupled to transmembrane movement of substances : IEA
  • BP: GO:0006810 : transport : IEA
  • CC: GO:0016021 : integral to membrane : IEA
  • MF: GO:0017111 : nucleoside-triphosphatase activity : IEA
  • BP: GO:0055085 : transmembrane transport : IEA
Domain Structure from CDD
  • P-loop NTPase: P-loop containing Nucleoside Triphosphate Hydrolases. This domain family is found in bacteria and archaea, and is approx.... (More)
  • ABC_ATPase: ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involv.... (More)
  • MdlB: ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]

See domain structure on NCBI Conserved Domain Database
Domain structure from Pfam
See domain structure on Pfam Database
Phenotype Description Expression
Class
Reference(s)
Candidate essential gene Identified as essential gene in one or more studies (see references) Knock out
PMID: 15547264
(candidate essential)