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Gene HP1272 from Helicobacter pylori 26695: NADH dehydrogenase subunit M
Member of NCBI Protein Clusters PRK05846(See COMBREX Page ) (See NCBI page)
NCBI Entrez GeneID 898821
UniProtKB accession
RefSeq Protein accession NP_208064.1 (PROVISIONAL)
Gene Symbol(s)
  • symbol: HP1272
  • locus tag: HP1272
Organism Helicobacter pylori 26695 (NCBI TaxID: 85962)
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Post a comment about this gene to appear on this page (info).
Source Predicted function(s)
NCBI Protein Cluster Prediction NADH dehydrogenase subunit M
Prof. Vitkup / Confidence:0.377 (References: 19935659, 16507154)
Berkeley Phylogenomics Group GO:0015453 oxidoreduction-driven active transmembrane transporter activity / (References: 19435885)
Berkeley Phylogenomics Group GO:0005515 protein binding / (References: 19435885)
Berkeley Phylogenomics Group GO:0048039 ubiquinone binding / (References: 19435885)
Functional Status blueblue (function predicted, no experimental evidence)
Source of prediction NCBI Protein Clusters info
EC number (See reaction via BRENDA)) (Source: NCBI RefSeq)
BLASTP hits to experimentally validated proteins
green nuoM from Rhodobacter capsulatus
(%_identity=39.53; E_val=3e-93; BitScore=337.0)

other hits with E-value < 1e-05
Share the same Pfam domain composition with the following experimentally validated proteins
green nuoN from Rhodobacter capsulatus

to see the rest 7 genes click here
GO terms
  • BP: GO:0055114 : oxidation reduction : IEA
  • CC: GO:0016020 : membrane : IEA
  • BP: GO:0042773 : ATP synthesis coupled electron transport : IEA
  • CC: GO:0016021 : integral to membrane : IEA
  • MF: GO:0016491 : oxidoreductase activity : IEA
  • MF: GO:0008137 : NADH dehydrogenase (ubiquinone) activity : IEA
Domain Structure from CDD
  • Oxidored_q1: NADH-Ubiquinone/plastoquinone (complex I), various chains. NADH dehydrogenase subunit 2; Provisional
  • PRK05846: NADH dehydrogenase subunit M; Reviewed

See domain structure on NCBI Conserved Domain Database
Domain structure from Pfam
See domain structure on Pfam Database
The table at right lists genes that may be "functionally linked to" (i.e., participate in a common biological process, or form a protein complex with) the subject gene of this page, as determined by two sequence-independent methods, including phylogenetic profiling and operon membership (determined by OperonDB). (Info.) These linkages may also be viewed graphically using the program VisANT, by clicking on the headers of the table. Note: VisANT requires Java. To install the latest version of Java, see
gene neighbourhoods
phylogenetic profile
HP1270NADH dehydrogenase subunit K
HP1271NADH dehydrogenase subunit L
HP1273NADH dehydrogenase subunit N
HP1274paralysed flagella protein (pflA)
HP1267NADH dehydrogenase subunit H  
HP1260NADH dehydrogenase subunit A  
HP1269NADH dehydrogenase subunit J  
Metabolic Annotation from Palsson Lab

Metabolic Reaction: NDH_1

NADH dehydrogenase (menaquinone) (complex I)
3 h[c] + mqn6[c] + nadph[c] -> 2 h[e] + mql6[c] + nadp[c]
Respiratory chain
Other Genes

Source: Ported to COMBREX by Segre's Lab