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Gene lpxK from Helicobacter pylori 26695: tetraacyldisaccharide 4'-kinase
Member of NCBI Protein Clusters PRK00652(See COMBREX Page ) (See NCBI page)
NCBI Entrez GeneID 898833
UniProtKB accession
RefSeq Protein accession NP_207126.1 (PROVISIONAL)
Gene Symbol(s)
  • symbol: lpxK
  • locus tag: HP0328
Organism Helicobacter pylori 26695 (NCBI TaxID: 85962)
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Source Predicted function(s)
NCBI Protein Cluster Prediction tetraacyldisaccharide 4'-kinase
Prof. Vitkup / Confidence:0.978 (References: 19935659, 16507154)
Functional Status blueblue (function predicted, no experimental evidence)
Source of prediction NCBI Protein Clusters info
EC number
BLASTP hits to experimentally validated proteins This gene does not have a BLAST match to any experimentally validated gene with an E value below 1e-5
GO terms
  • MF: GO:0000166 : nucleotide binding : IEA
  • MF: GO:0009029 : tetraacyldisaccharide 4'-kinase activity : IEA
  • MF: GO:0005524 : ATP binding : IEA
  • BP: GO:0008610 : lipid biosynthetic process : IEA
  • MF: GO:0016740 : transferase activity : IEA
  • BP: GO:0009245 : lipid A biosynthetic process : IEA
  • MF: GO:0016301 : kinase activity : IEA
Domain Structure from CDD
  • LpxK: Tetraacyldisaccharide-1-P 4'-kinase. tetraacyldisaccharide 4'-kinase; Reviewed
  • LpxK: Tetraacyldisaccharide-1-P 4'-kinase [Cell envelope biogenesis, outer membrane]

See domain structure on NCBI Conserved Domain Database
Domain structure from Pfam
See domain structure on Pfam Database
The table at right lists genes that may be "functionally linked to" (i.e., participate in a common biological process, or form a protein complex with) the subject gene of this page, as determined by two sequence-independent methods, including phylogenetic profiling and operon membership (determined by OperonDB). (Info.) These linkages may also be viewed graphically using the program VisANT, by clicking on the headers of the table. Note: VisANT requires Java. To install the latest version of Java, see
phylogenetic profile
HP0329NAD synthetase
HP1489lipase-like protein 
HP1445biopolymer transport protein (exbB) 
lpxDUDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltra 
HP09573-deoxy-D-manno-octulosonic-acid transferase 
HP00032-dehydro-3-deoxyphosphooctonate aldolase 
HP1130biopolymer transport protein (exbB) 
HP0280lipid A biosynthesis lauroyl acyltransferase 
HP0703response regulator 
HP0595hypothetical protein 
lpxCUDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine d 
HP1129biopolymer transport protein (exbD) 
HP1446biopolymer transport protein (exbD) 
HP1375UDP-N-acetylglucosamine acyltransferase 
HP0605hypothetical protein 
HP02303-deoxy-manno-octulosonate cytidylyltransferase 
lpxBipid-A-disaccharide synthase 
HP1339biopolymer transport protein (exbB) 
HP1125peptidoglycan associated lipoprotein precursor (om 
HP1340biopolymer transport protein (exbD)