Combrex Enter Keyword, gene symbol, or identifier (more options; Help )
Enter species name
Gene functional status (select)
Phenotype association (select)[View list of phenotypes]
Check to restrict search to:
Genes in Category A-C and Emerging/Re-Emerging pathogens
Genes in curated Protein Clusters
Genes with predictions submitted to COMBREX
P
Genes with solved structures in PDB
S
Genes with Pfam domains shared with human proteins
H
Genes with products purified by PSI
U
Genes cloned by PSI
C
close options

 

Gene HP1220 from Helicobacter pylori 26695: ABC transporter, ATP-binding protein (yhcG)
Member of NCBI Protein Clusters CLSK496416(See COMBREX Page ) (See NCBI page)
NCBI Entrez GeneID 898844
UniProtKB accession
RefSeq Protein accession NP_208012.1 (PROVISIONAL)
Gene Symbol(s)
  • symbol: HP1220
  • locus tag: HP1220
Organism Helicobacter pylori 26695 (NCBI TaxID: 85962)
Initiate the grant application process for experimentally validating this gene (Important notice about COMBREX grants.)
Contribute a predicted function for this gene (free text, GO terms, or EC number) (info). Be sure to check the list of current predicted functions in the section immediately below beforehand.
Nominate this gene for the Gold Standard Gene Database (if you believe it has been experimentally validated) (info).
Post a comment about this gene to appear on this page (info).
Source Predicted function(s)
NCBI Protein Cluster Prediction ABC transporter, ATP-binding protein
Prof. David Horn 3.6.3: acting on acid anhydrides, catalyzing transmembrane movement / (References: 20034383)
Prof. Vitkup 3.6.3.31 / Confidence:0.026 (References: 19935659, 16507154)
Functional Status blueblue (function predicted, no experimental evidence)
Source of prediction NCBI Protein Clusters info
BLASTP hits to experimentally validated proteins
green ecsA from Bacillus subtilis subsp. subtilis str. 168
(%_identity=30.0; E_val=4e-21; BitScore=96.3)

other hits with E-value < 1e-05
Share the same Pfam domain composition with the following experimentally validated proteins
green ftsE from Bacillus subtilis subsp. subtilis str. 168

to see the rest 79 genes click here
GO terms
  • MF: GO:0016887 : ATPase activity : IEA
  • MF: GO:0000166 : nucleotide binding : IEA
  • MF: GO:0005524 : ATP binding : IEA
  • MF: GO:0017111 : nucleoside-triphosphatase activity : IEA
Domain Structure from CDD
  • ZnuC: ABC-type Mn/Zn transport systems, ATPase component [Inorganic ion transport and metabolism]
  • ABC_DR_subfamily_A: This family of ATP-binding proteins belongs to a multisubunit transporter involved in drug resistance (BcrA and DrrA), n.... (More)

See domain structure on NCBI Conserved Domain Database
Domain structure from Pfam
See domain structure on Pfam Database
The table at right lists genes that may be "functionally linked to" (i.e., participate in a common biological process, or form a protein complex with) the subject gene of this page, as determined by two sequence-independent methods, including phylogenetic profiling and operon membership (determined by OperonDB). (Info.) These linkages may also be viewed graphically using the program VisANT, by clicking on the headers of the table. Note: VisANT requires Java. To install the latest version of Java, see www.java.com
 OperonDB
HP1222D-lactate dehydrogenase (dld)
 
HP1221hypothetical protein