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Gene HP0746 from Helicobacter pylori 26695: hypothetical protein

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Summary
Member of NCBI Protein Clusters CLSK872436(See COMBREX Page ) (See NCBI page)
NCBI Entrez GeneID 898850
UniProtKB accession
RefSeq Protein accession NP_207539.1 (PROVISIONAL)
Gene Symbol(s)
  • symbol: HP0746
  • locus tag: HP0746
Organism Helicobacter pylori 26695 (NCBI TaxID: 85962)

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Actions You Can Take
Initiate the grant application process for experimentally validating this gene (Important notice about COMBREX grants.)
Contribute a predicted function for this gene (free text, GO terms, or EC number) (info). Be sure to check the list of current predicted functions in the section immediately below beforehand.
Nominate this gene for the Gold Standard Gene Database (if you believe it has been experimentally validated) (info).
Post a comment about this gene to appear on this page (info).

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Function Predictions
Source Predicted function(s)
NCBI Protein Cluster Prediction fibronectin type III domain-containing protein
Prof. Vitkup 3.1.1.75 / Confidence:0.008 (References: 19935659, 16507154)
Berkeley Phylogenomics Group GO:0005515 protein binding / (References: 19435885)
Berkeley Phylogenomics Group GO:0004725 protein tyrosine phosphatase activity / (References: 19435885)
Berkeley Phylogenomics Group 3.1.1.75: Poly(3-hydroxybutyrate) depolymerase. / (References: 19435885)
Berkeley Phylogenomics Group 3.2.1.91: Cellulose 1,4-beta-cellobiosidase. / (References: 19435885)

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Supporting Functional Information
Functional Status blueblue (function predicted, no experimental evidence)
Source of prediction NCBI Protein Clusters info
BLASTP hits to experimentally validated proteins This gene does not have a BLAST match to any experimentally validated gene with an E value below 1e-5
Domain Structure from CDD
  • FN3: Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fib.... (More)
  • COG3401: Fibronectin type 3 domain-containing protein [General function prediction only]

See domain structure on NCBI Conserved Domain Database
Domain structure from Pfam
See domain structure on Pfam Database

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Functionally Linked Genes
The table at right lists genes that may be "functionally linked to" (i.e., participate in a common biological process, or form a protein complex with) the subject gene of this page, as determined by two sequence-independent methods, including phylogenetic profiling and operon membership (determined by OperonDB). (Info.) These linkages may also be viewed graphically using the program VisANT, by clicking on the headers of the table. Note: VisANT requires Java. To install the latest version of Java, see www.java.com
 OperonDB
HP0745hypothetical protein
 
HP0748cell division protein (ftsE)
 
trmBtRNA (guanine-N(7)-)-methyltransferase
 

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Phenotype data
Phenotype Description Expression
Class		 Reference(s)
Candidate essential gene Identified as essential gene in one or more studies (see references) Knock out
PMID: 15547264
(candidate essential)