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Gene gltX from Helicobacter pylori 26695: glutamyl-tRNA synthetase
Member of NCBI Protein Clusters PRK01406(See COMBREX Page ) (See NCBI page)
NCBI Entrez GeneID 898901
UniProtKB accession
RefSeq Protein accession NP_207274.1 (PROVISIONAL)
Gene Symbol(s)
  • symbol: gltX
  • locus tag: HP0476
Organism Helicobacter pylori 26695 (NCBI TaxID: 85962)
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Source Predicted function(s)
NCBI Protein Cluster Prediction glutamyl-tRNA synthetase
Prof. Vitkup / Confidence:0.564 (References: 19935659, 16507154)
Berkeley Phylogenomics Group GO:0042802 identical protein binding / (References: 19435885)
Berkeley Phylogenomics Group Glutamate--tRNA ligase. / (References: 19435885)
Berkeley Phylogenomics Group GO:0005515 protein binding / (References: 19435885)
Berkeley Phylogenomics Group GO:0004819 glutamine-tRNA ligase activity / (References: 19435885)
Berkeley Phylogenomics Group GO:0004818 glutamate-tRNA ligase activity / (References: 19435885)
Berkeley Phylogenomics Group GO:0004827 proline-tRNA ligase activity / (References: 19435885)
Berkeley Phylogenomics Group GO:0005524 ATP binding / (References: 19435885)
Berkeley Phylogenomics Group GO:0008270 zinc ion binding / (References: 19435885)
Berkeley Phylogenomics Group Glutamine--tRNA ligase. / (References: 19435885)
Functional Status blueblue (function predicted, no experimental evidence)
Source of prediction NCBI Protein Clusters info
EC number
BLASTP hits to experimentally validated proteins
green gltX from Escherichia coli str. K-12 substr. MG1655
(%_identity=42.95; E_val=7e-103; BitScore=369.0)

other hits with E-value < 1e-05
Share the same Pfam domain composition with the following experimentally validated proteins
green gltX from Thermosynechococcus elongatus BP-1

to see the rest 6 genes click here
GO terms
  • MF: GO:0005524 : ATP binding : IEA
  • MF: GO:0016874 : ligase activity : IEA
  • BP: GO:0006412 : translation : IEA
  • MF: GO:0004818 : glutamate-tRNA ligase activity : IEA
  • BP: GO:0006418 : tRNA aminoacylation for protein translation : IEA
  • BP: GO:0006424 : glutamyl-tRNA aminoacylation : IEA
  • CC: GO:0005737 : cytoplasm : IEA
  • MF: GO:0000166 : nucleotide binding : IEA
  • MF: GO:0004812 : aminoacyl-tRNA ligase activity : IEA
Domain Structure from CDD
  • gltX: glutamyl-tRNA synthetase; Reviewed
  • GluRS_core: catalytic core domain of descriminating glutamyl-tRNA synthetase. Descriminating Glutamyl-tRNA synthetase (GluRS) cataly.... (More)

See domain structure on NCBI Conserved Domain Database
Domain structure from Pfam
See domain structure on Pfam Database
Metabolic Annotation from Palsson Lab

Metabolic Reaction: GLUTRS

Glutamyl-tRNA synthetase
atp[c] + glu-DASH-L[c] + trnaglu[c] -> amp[c] + glutrna[c] + ppi[c]
Heme biosynthesis
Other Genes

Source: Ported to COMBREX by Segre's Lab