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Gene HP0687 from Helicobacter pylori 26695: iron(II) transport protein (feoB)
Member of NCBI Protein Clusters CLSK496156(See COMBREX Page ) (See NCBI page)
NCBI Entrez GeneID 898903
UniProtKB accession
RefSeq Protein accession NP_207481.1 (PROVISIONAL)
Gene Symbol(s)
  • symbol: HP0687
  • locus tag: HP0687
Organism Helicobacter pylori 26695 (NCBI TaxID: 85962)
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Contribute a predicted function for this gene (free text, GO terms, or EC number) (info). Be sure to check the list of current predicted functions in the section immediately below beforehand.
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Post a comment about this gene to appear on this page (info).
Source Predicted function(s)
NCBI Protein Cluster Prediction iron(II) transport protein
Berkeley Phylogenomics Group GO:0042803 protein homodimerization activity / (References: 19435885)
Berkeley Phylogenomics Group GO:0004888 transmembrane receptor activity / (References: 19435885)
Berkeley Phylogenomics Group GO:0051219 phosphoprotein binding / (References: 19435885)
Berkeley Phylogenomics Group GO:0030234 enzyme regulator activity / (References: 19435885)
Berkeley Phylogenomics Group GO:0003924 GTPase activity / (References: 19435885)
Berkeley Phylogenomics Group GO:0042802 identical protein binding / (References: 19435885)
Berkeley Phylogenomics Group GO:0008017 microtubule binding / (References: 19435885)
Berkeley Phylogenomics Group GO:0032947 protein complex scaffold / (References: 19435885)
Berkeley Phylogenomics Group GO:0005545 phosphatidylinositol binding / (References: 19435885)
Berkeley Phylogenomics Group GO:0046982 protein heterodimerization activity / (References: 19435885)
Berkeley Phylogenomics Group GO:0019003 GDP binding / (References: 19435885)
Berkeley Phylogenomics Group GO:0005525 GTP binding / (References: 19435885)
Berkeley Phylogenomics Group GO:0003779 actin binding / (References: 19435885)
Berkeley Phylogenomics Group GO:0005515 protein binding / (References: 19435885)
Berkeley Phylogenomics Group GO:0031625 ubiquitin protein ligase binding / (References: 19435885)
Berkeley Phylogenomics Group GO:0003723 RNA binding / (References: 19435885)
Source References Functional description
GSDB
[PMID: 10931324]
Ferrous iron transport protein B (source organism: Helicobacter pylori (Campylobacter pylori).; strain specific ID: ATCC 43504 / NCTC 11637 / JCM 7653 / RPH 13487)
Functional Status greenGreen (experimental evidence, uncurated)
GO terms
  • MF: GO:0001882 : nucleoside binding : IEA
  • MF: GO:0005524 : ATP binding : IEA
  • BP: GO:0006811 : ion transport : IEA
  • MF: GO:0015093 : ferrous iron transmembrane transporter activity : IEA
  • CC: GO:0016021 : integral to membrane : IEA
  • CC: GO:0005886 : plasma membrane : IEA
  • CC: GO:0016020 : membrane : IEA
  • BP: GO:0006826 : iron ion transport : IEA
  • MF: GO:0000166 : nucleotide binding : IEA
  • BP: GO:0015684 : ferrous iron transport : IEA
  • MF: GO:0005525 : GTP binding : IEA
  • BP: GO:0006810 : transport : IEA
Domain Structure from CDD
  • FeoB: Ferrous iron transport protein B (FeoB) subfamily. E. coli has an iron(II) transport system, known as feo, which may ma.... (More)
  • feoB: ferrous iron transporter FeoB. FeoB (773 amino acids in E. coli), a cytoplasmic membrane protein required for iron(II) u.... (More)
  • Gate: Nucleoside recognition. hypothetical protein; Provisional
  • FeoB_C: Ferrous iron transport protein B C terminus. Escherichia coli has an iron(II) transport system (feo) which may make an i.... (More)

See domain structure on NCBI Conserved Domain Database
Domain structure from Pfam
See domain structure on Pfam Database
Based on the function of this gene, COMBREX predictions were made to the following related genes (mouse over gene symbol for details) [Download ]
feoB (3) , HPAG1_0670 , HPSH_03430
The table at right lists genes that may be "functionally linked to" (i.e., participate in a common biological process, or form a protein complex with) the subject gene of this page, as determined by two sequence-independent methods, including phylogenetic profiling and operon membership (determined by OperonDB). (Info.) These linkages may also be viewed graphically using the program VisANT, by clicking on the headers of the table. Note: VisANT requires Java. To install the latest version of Java, see www.java.com
 OperonDB
HP0686iron(III) dicitrate transport protein (fecA)
 
Metabolic Annotation from Palsson Lab

Metabolic Reaction: FE2abc

Name
iron (II) transport via ABC system
Formula
atp[c] + fe2[e] + h2o[c] -> adp[c] + fe2[c] + h[c] + pi[c]
Pathway
Transport

Source: Ported to COMBREX by Segre's Lab