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Gene secA from Helicobacter pylori 26695: preprotein translocase subunit SecA
Member of NCBI Protein Clusters PRK12904(See COMBREX Page ) (See NCBI page)
NCBI Entrez GeneID 898905
UniProtKB accession
RefSeq Protein accession NP_207579.1 (PROVISIONAL)
Gene Symbol(s)
  • symbol: secA
  • locus tag: HP0786
  • aliases: azi, div
Organism Helicobacter pylori 26695 (NCBI TaxID: 85962)
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Source Predicted function(s)
NCBI Protein Cluster Prediction preprotein translocase subunit SecA
Berkeley Phylogenomics Group GO:0005515 protein binding / (References: 19435885)
Berkeley Phylogenomics Group GO:0000287 magnesium ion binding / (References: 19435885)
Functional Status blueblue (function predicted, no experimental evidence)
Source of prediction NCBI Protein Clusters info
BLASTP hits to experimentally validated proteins
green secA from Escherichia coli str. K-12 substr. MG1655
(%_identity=48.8; E_val=0.0; BitScore=803.0)

other hits with E-value < 1e-05
Share the same Pfam domain composition with the following experimentally validated proteins
green secA from Haemophilus influenzae Rd KW20

to see the rest 2 gene click here
GO terms
  • MF: GO:0046872 : metal ion binding : IEA
  • MF: GO:0005524 : ATP binding : IEA
  • BP: GO:0017038 : protein import : IEA
  • BP: GO:0006886 : intracellular protein transport : IEA
  • MF: GO:0005515 : protein binding : IEA
  • CC: GO:0005886 : plasma membrane : IEA
  • BP: GO:0065002 : intracellular protein transmembrane transport : IEA
  • BP: GO:0055085 : transmembrane transport : IEA
  • CC: GO:0016020 : membrane : IEA
  • MF: GO:0000166 : nucleotide binding : IEA
  • BP: GO:0015031 : protein transport : IEA
  • CC: GO:0005737 : cytoplasm : IEA
  • BP: GO:0006810 : transport : IEA
  • BP: GO:0006605 : protein targeting : IEA
Domain Structure from CDD
  • SecA_PP_bind: SecA preprotein cross-linking domain. The SecA ATPase is involved in the insertion and retraction of preproteins through.... (More)
  • PRK10396: hypothetical protein; Provisional
  • secA2: accessory Sec system translocase SecA2. Members of this protein family are homologous to SecA and part of the accessory .... (More)
  • SEC-C: SEC-C motif. hypothetical protein; Provisional
  • HELICc: Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A.... (More)
  • SecA_SW: SecA Wing and Scaffold domain. SecA protein binds to the plasma membrane where it interacts with proOmpA to support tran.... (More)

See domain structure on NCBI Conserved Domain Database
Domain structure from Pfam
See domain structure on Pfam Database
The table at right lists genes that may be "functionally linked to" (i.e., participate in a common biological process, or form a protein complex with) the subject gene of this page, as determined by two sequence-independent methods, including phylogenetic profiling and operon membership (determined by OperonDB). (Info.) These linkages may also be viewed graphically using the program VisANT, by clicking on the headers of the table. Note: VisANT requires Java. To install the latest version of Java, see www.java.com
 OperonDB
phylogenetic profile
HP0788hypothetical protein
 
 
HP0787hypothetical protein
 
 
trmDtRNA (guanine-N(1)-)-methyltransferase 
 
secEpreprotein translocase membrane subunit 
 
rplT50S ribosomal protein L20 
 
HP1362replicative DNA helicase 
 
dnaEDNA polymerase III subunit alpha 
 
rpmI50S ribosomal protein L35 
 
HP1247DNA polymerase III subunit delta 
 
ligANAD-dependent DNA ligase LigA 
 
HP1448ribonuclease P, protein component (rnpA) 
 
rplI50S ribosomal protein L9 
 
rplU50S ribosomal protein L21 
 
HP1051hypothetical protein 
 
ruvAHolliday junction DNA helicase RuvA 
 
tigtrigger factor 
 
mraWS-adenosyl-methyltransferase MraW 
 
HP0717DNA polymerase III subunits gamma and tau 
 
tsfelongation factor Ts 
 
HP0955prolipoprotein diacylglyceryl transferase 
 
rbfAribosome-binding factor A 
 
infCtranslation initiation factor IF-3 
 
rpsT30S ribosomal protein S20 
 
rpmE50S ribosomal protein L31 
 
HP0088RNA polymerase sigma factor RpoD 
 
defpeptide deformylase 
 
nusBtranscription antitermination protein NusB 
 
ruvBHolliday junction DNA helicase RuvB 
 
smpBSsrA-binding protein 
 
dnaAchromosomal replication initiation protein 
 
lspAlipoprotein signal peptidase