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Gene clpP from Helicobacter pylori 26695: ATP-dependent Clp protease proteolytic subunit
Member of NCBI Protein Clusters PRK00277(See COMBREX Page ) (See NCBI page)
NCBI Entrez GeneID 898920
UniProtKB accession
RefSeq Protein accession NP_207587.1 (PROVISIONAL)
Gene Symbol(s)
  • symbol: clpP
  • locus tag: HP0794
Organism Helicobacter pylori 26695 (NCBI TaxID: 85962)
Other Cross References:
  • S
    Structure(s) available in PDB: 2ZL0 2ZL2 2ZL3 2ZL4
  • C
    Gene cloned by a participant in the Protein Structure Initiative (PSI): TargetDB. (To obtain a clone, please contact the PSI:Biology-Materials Repository.)
  • U
    Protein purified by a participant in the Protein Structure Initiative (PSI): TargetDB. (If you are interested in collaborating to obtain the protein, please contact the Northeast Structural Genomics consortium).
  • Protein described in EcoCyc:
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Contribute a predicted function for this gene (free text, GO terms, or EC number) (info). Be sure to check the list of current predicted functions in the section immediately below beforehand.
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Post a comment about this gene to appear on this page (info).
Source Predicted function(s)
NCBI Protein Cluster Prediction ATP-dependent Clp protease proteolytic subunit
Berkeley Phylogenomics Group GO:0005515 protein binding / (References: 19435885)
Berkeley Phylogenomics Group Endopeptidase Clp. / (References: 19435885)
Berkeley Phylogenomics Group GO:0008270 zinc ion binding / (References: 19435885)
Berkeley Phylogenomics Group GO:0050897 cobalt ion binding / (References: 19435885)
Functional Status blueblue (function predicted, no experimental evidence)
Source of prediction NCBI Protein Clusters info
EC number
BLASTP hits to experimentally validated proteins This gene does not have a BLAST match to any experimentally validated gene with an E value below 1e-5
Share the same Pfam domain composition with the following experimentally validated proteins
green clpP from Escherichia coli str. K-12 substr. MG1655

to see the rest 2 gene click here
GO terms
  • MF: GO:0008236 : serine-type peptidase activity : IEA
  • MF: GO:0000166 : nucleotide binding : IEA
  • CC: GO:0005737 : cytoplasm : IEA
  • MF: GO:0005524 : ATP binding : IEA
  • BP: GO:0006508 : proteolysis : IEA
  • MF: GO:0008233 : peptidase activity : IEA
  • MF: GO:0016787 : hydrolase activity : IEA
  • MF: GO:0004252 : serine-type endopeptidase activity : IEA
Domain Structure from CDD
  • S14_ClpP_2: Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease. Clp protease (caseinolytic protease;.... (More)

See domain structure on NCBI Conserved Domain Database
Domain structure from Pfam
See domain structure on Pfam Database
The table at right lists genes that may be "functionally linked to" (i.e., participate in a common biological process, or form a protein complex with) the subject gene of this page, as determined by two sequence-independent methods, including phylogenetic profiling and operon membership (determined by OperonDB). (Info.) These linkages may also be viewed graphically using the program VisANT, by clicking on the headers of the table. Note: VisANT requires Java. To install the latest version of Java, see
gene neighbourhoods
phylogenetic profile
HP0792sigma-54 interacting protein
defpeptide deformylase
tigtrigger factor
HP0796outer membrane protein (omp18)
HP0810hypothetical protein  
HP1556cell division protein (ftsI)  
HP1470DNA polymerase I (polA)  
clpXATP-dependent protease ATP-binding subunit ClpX  
HP0743rod shape-determining protein (mreB)  
HP1149hypothetical protein  
HP1560cell division protein (ftsW)  
yajCpreprotein translocase subunit YajC  
murGundecaprenyldiphospho-muramoylpentapeptide beta-N-  
prfBpeptide chain release factor 2  
HP0648UDP-N-acetylglucosamine 1-carboxyvinyltransferase  
HP0683UDP-N-acetylglucosamine pyrophosphorylase (glmU)  
HP1226coproporphyrinogen III oxidase  
rpsA30S ribosomal protein S1  
murBUDP-N-acetylenolpyruvoylglucosamine reductase  
HP1543toxR-activated gene (tagE)  
HP0223DNA repair protein RadA  
HP1213polynucleotide phosphorylase/polyadenylase  
HP1565penicillin-binding protein 2 (pbp2)  
miaAtRNA delta(2)-isopentenylpyrophosphate transferase  
HP0387primosome assembly protein PriA  
HP1365response regulator  
HP1544toxR-activated gene (tagE)  
HP1043response regulator  
HP1459hypothetical protein  
HP0750hypothetical protein  
HP0506hypothetical protein  
HP0640poly(A) polymerase (papS)  
murDUDP-N-acetylmuramoyl-L-alanyl-D-glutamate syntheta  
HP1054hypothetical protein  
HP0665coproporphyrinogen III oxidase  
HP0166response regulator (ompR)  
murCUDP-N-acetylmuramate--L-alanine ligase  
HP1541transcription-repair coupling factor (trcF)  
HP1523ATP-dependent DNA helicase RecG  
ddlD-alanyl-alanine synthetase A  
secGpreprotein translocase subunit SecG