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Gene HP0630 from Helicobacter pylori 26695: modulator of drug activity (mda66)
Member of NCBI Protein Clusters CLSK694698(See COMBREX Page ) (See NCBI page)
NCBI Entrez GeneID 898924
UniProtKB accession
RefSeq Protein accession NP_207424.1 (PROVISIONAL)
Gene Symbol(s)
  • symbol: HP0630
  • locus tag: HP0630
Organism Helicobacter pylori 26695 (NCBI TaxID: 85962)
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Source Predicted function(s)
NCBI Protein Cluster Prediction modulator of drug activity
Berkeley Phylogenomics Group Ribosyldihydronicotinamide dehydrogenase (quinone). / (References: 19435885)
Berkeley Phylogenomics Group NAD(P)H dehydrogenase (quinone). / (References: 19435885)
Berkeley Phylogenomics Group GO:0003955 NAD(P)H dehydrogenase (quinone) activity / (References: 19435885)
Berkeley Phylogenomics Group GO:0010181 FMN binding / (References: 19435885)
Berkeley Phylogenomics Group GO:0050446 azobenzene reductase activity / (References: 19435885)
Functional Status blueblue (function predicted, no experimental evidence)
Source of prediction NCBI Protein Clusters info
BLASTP hits to experimentally validated proteins This gene does not have a BLAST match to any experimentally validated gene with an E value below 1e-5
Share the same Pfam domain composition with the following experimentally validated proteins
green yvaB from Bacillus subtilis subsp. subtilis str. 168

to see the rest 6 genes click here
GO terms
  • BP: GO:0055114 : oxidation reduction : IEA
  • MF: GO:0016491 : oxidoreductase activity : IEA
  • MF: GO:0050662 : coenzyme binding : IEA
  • MF: GO:0009055 : electron carrier activity : IEA
Domain Structure from CDD
  • FMN_red: NADPH-dependent FMN reductase. azoreductase; Provisional

See domain structure on NCBI Conserved Domain Database
Domain structure from Pfam
See domain structure on Pfam Database
Metabolic Annotation from Palsson Lab

Metabolic Reaction: NADPHQR

NADPH Quinone Reductase
h[c] + mqn6[c] + nadph[c] -> mql6[c] + nadp[c]
Respiratory chain

Source: Ported to COMBREX by Segre's Lab