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Gene HP0293 from Helicobacter pylori 26695: para-aminobenzoate synthetase (pabB)
Member of NCBI Protein Clusters CLSK872329(See COMBREX Page ) (See NCBI page)
NCBI Entrez GeneID 899198
UniProtKB accession
RefSeq Protein accession NP_207091.1 (PROVISIONAL)
Gene Symbol(s)
  • symbol: HP0293
  • locus tag: HP0293
Organism Helicobacter pylori 26695 (NCBI TaxID: 85962)
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Source Predicted function(s)
NCBI Protein Cluster Prediction para-aminobenzoate synthase glutamine amidotransferase, component I
Prof. Vitkup / Confidence:0.073 (References: 19935659, 16507154)
Berkeley Phylogenomics Group GO:0030170 pyridoxal phosphate binding / (References: 19435885)
Berkeley Phylogenomics Group GO:0008696 4-amino-4-deoxychorismate lyase activity / (References: 19435885)
Berkeley Phylogenomics Group GO:0047810 D-alanine:2-oxoglutarate aminotransferase activity / (References: 19435885)
Berkeley Phylogenomics Group GO:0004084 branched-chain-amino-acid transaminase activity / (References: 19435885)
Berkeley Phylogenomics Group GO:0010326 methionine-oxo-acid transaminase activity / (References: 19435885)
Berkeley Phylogenomics Group GO:0042802 identical protein binding / (References: 19435885)
Berkeley Phylogenomics Group Aminodeoxychorismate lyase. / (References: 19435885)
Berkeley Phylogenomics Group Branched-chain-amino-acid transaminase. / (References: 19435885)
Functional Status blueblue (function predicted, no experimental evidence)
Source of prediction NCBI Protein Clusters info
BLASTP hits to experimentally validated proteins This gene does not have a BLAST match to any experimentally validated gene with an E value below 1e-5
GO terms
  • BP: GO:0008152 : metabolic process : IEA
  • MF: GO:0003824 : catalytic activity : IEA
  • BP: GO:0009058 : biosynthetic process : IEA
Domain Structure from CDD
  • Chorismate_bind: chorismate binding enzyme. para-aminobenzoate synthase component I; Validated
  • PLPDE_IV: N/A. aminotransferase; Provisional
  • PRK07508: aminodeoxychorismate synthase; Provisional

See domain structure on NCBI Conserved Domain Database
Domain structure from Pfam
See domain structure on Pfam Database
The table at right lists genes that may be "functionally linked to" (i.e., participate in a common biological process, or form a protein complex with) the subject gene of this page, as determined by two sequence-independent methods, including phylogenetic profiling and operon membership (determined by OperonDB). (Info.) These linkages may also be viewed graphically using the program VisANT, by clicking on the headers of the table. Note: VisANT requires Java. To install the latest version of Java, see
phylogenetic profile
domain fusion
HP0291hypothetical protein
HP0292hypothetical protein
amiEacylamide amidohydrolase
HP1281anthranilate synthase component II 
HP1282anthranilate synthase component I  
Metabolic Annotation from Palsson Lab

Metabolic Reaction: PABB

chor[c] + nh4[c] -> 4adcho[c] + h2o[c]
Folate Biosynthesis

Source: Ported to COMBREX by Segre's Lab