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Gene rnhA from Helicobacter pylori 26695: ribonuclease H
Member of NCBI Protein Clusters PRK00203(See COMBREX Page ) (See NCBI page)
NCBI Entrez GeneID 899305
UniProtKB accession
RefSeq Protein accession NP_207455.1 (PROVISIONAL)
Gene Symbol(s)
  • symbol: rnhA
  • locus tag: HP0661
Organism Helicobacter pylori 26695 (NCBI TaxID: 85962)
Other Cross References:
  • S
    Structure(s) available in PDB:
  • C
    Gene cloned by a participant in the Protein Structure Initiative (PSI): TargetDB. (To obtain a clone, please contact the PSI:Biology-Materials Repository.)
  • U
    Protein purified by a participant in the Protein Structure Initiative (PSI): TargetDB. (If you are interested in collaborating to obtain the protein, please contact the Northeast Structural Genomics consortium).
  • Protein described in EcoCyc:
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Contribute a predicted function for this gene (free text, GO terms, or EC number) (info). Be sure to check the list of current predicted functions in the section immediately below beforehand.
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Post a comment about this gene to appear on this page (info).
Source Predicted function(s)
NCBI Protein Cluster Prediction ribonuclease H
Berkeley Phylogenomics Group GO:0005515 protein binding / (References: 19435885)
Berkeley Phylogenomics Group GO:0042803 protein homodimerization activity / (References: 19435885)
Berkeley Phylogenomics Group GO:0004523 ribonuclease H activity / (References: 19435885)
Functional Status blueblue (function predicted, no experimental evidence)
Source of prediction NCBI Protein Clusters info
EC number
BLASTP hits to experimentally validated proteins
green rnhA from Escherichia coli str. K-12 substr. MG1655
(%_identity=53.57; E_val=2e-38; BitScore=152.0)

other hits with E-value < 1e-05
Share the same Pfam domain composition with the following experimentally validated proteins
green ypdQ from Bacillus subtilis subsp. subtilis str. 168

to see the rest 3 genes click here
GO terms
  • MF: GO:0000287 : magnesium ion binding : IEA
  • CC: GO:0005737 : cytoplasm : IEA
  • MF: GO:0046872 : metal ion binding : IEA
  • MF: GO:0004519 : endonuclease activity : IEA
  • BP: GO:0006401 : RNA catabolic process : IEA
  • MF: GO:0016787 : hydrolase activity : IEA
  • MF: GO:0003676 : nucleic acid binding : IEA
  • MF: GO:0004523 : ribonuclease H activity : IEA
  • MF: GO:0004518 : nuclease activity : IEA
Domain Structure from CDD
  • RnaseH: RNase H (RNase HI) is an endonuclease that cleaves the RNA strand of an RNA/DNA hybrid in a not sequence-specific manner.... (More)

See domain structure on NCBI Conserved Domain Database
Domain structure from Pfam
See domain structure on Pfam Database
The table at right lists genes that may be "functionally linked to" (i.e., participate in a common biological process, or form a protein complex with) the subject gene of this page, as determined by two sequence-independent methods, including phylogenetic profiling and operon membership (determined by OperonDB). (Info.) These linkages may also be viewed graphically using the program VisANT, by clicking on the headers of the table. Note: VisANT requires Java. To install the latest version of Java, see www.java.com
 OperonDB
HP0663chorismate synthase
 
rncribonuclease III
 
HP0659hypothetical protein
 
HP0660hypothetical protein
 
Phenotype Description Expression
Class
Reference(s)
Candidate essential gene Identified as essential gene in one or more studies (see references) Knock out
PMID: 15547264
(candidate essential)