Combrex Enter Keyword, gene symbol, or identifier (more options; Help )
Enter species name
Gene functional status (select)
Phenotype association (select)[View list of phenotypes]
Check to restrict search to:
Genes in Category A-C and Emerging/Re-Emerging pathogens
Genes in curated Protein Clusters
Genes with predictions submitted to COMBREX
Genes with solved structures in PDB
Genes with Pfam domains shared with human proteins
Genes with products purified by PSI
Genes cloned by PSI
close options


Gene prmA from Helicobacter pylori 26695: ribosomal protein L11 methyltransferase
Member of NCBI Protein Clusters PRK00517(See COMBREX Page ) (See NCBI page)
NCBI Entrez GeneID 899604
UniProtKB accession
RefSeq Protein accession NP_207859.1 (PROVISIONAL)
Gene Symbol(s)
  • symbol: prmA
  • locus tag: HP1068
Organism Helicobacter pylori 26695 (NCBI TaxID: 85962)
Initiate the grant application process for experimentally validating this gene (Important notice about COMBREX grants.)
Contribute a predicted function for this gene (free text, GO terms, or EC number) (info). Be sure to check the list of current predicted functions in the section immediately below beforehand.
Nominate this gene for the Gold Standard Gene Database (if you believe it has been experimentally validated) (info).
Post a comment about this gene to appear on this page (info).
Source Predicted function(s)
NCBI Protein Cluster Prediction ribosomal protein L11 methyltransferase
Prof. Vitkup / Confidence:0.104 (References: 19935659, 16507154)
Combrex_01 ortholog of E. coli prmA / Anton BP unpublished
Functional Status blueblue (function predicted, no experimental evidence)
Source of prediction NCBI Protein Clusters info
BLASTP hits to experimentally validated proteins This gene does not have a BLAST match to any experimentally validated gene with an E value below 1e-5
Share the same Pfam domain composition with the following experimentally validated proteins
green prmA from Thermus thermophilus HB8

to see the rest 2 gene click here
GO terms
  • CC: GO:0005737 : cytoplasm : IEA
  • BP: GO:0006479 : protein amino acid methylation : IEA
  • MF: GO:0008168 : methyltransferase activity : IEA
  • MF: GO:0016740 : transferase activity : IEA
  • MF: GO:0008276 : protein methyltransferase activity : IEA
Domain Structure from CDD
  • prmA: ribosomal protein L11 methyltransferase. Ribosomal protein L11 methyltransferase is an S-adenosyl-L-methionine-dependent.... (More)
  • AdoMet_MTases: S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-.... (More)

See domain structure on NCBI Conserved Domain Database
Domain structure from Pfam
See domain structure on Pfam Database
The table at right lists genes that may be "functionally linked to" (i.e., participate in a common biological process, or form a protein complex with) the subject gene of this page, as determined by two sequence-independent methods, including phylogenetic profiling and operon membership (determined by OperonDB). (Info.) These linkages may also be viewed graphically using the program VisANT, by clicking on the headers of the table. Note: VisANT requires Java. To install the latest version of Java, see
phylogenetic profile
HP1067chemotaxis protein (cheY)
HP1069cell division protein (ftsH)
HP1070hypothetical protein
HP1576ABC transporter ATP-binding protein 
fabZ(3R)-hydroxymyristoyl-ACP dehydratase 
queAS-adenosylmethionine:tRNA ribosyltransferase-isome 
HP0700diacylglycerol kinase (dgkA)