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Gene HP1082 from Helicobacter pylori 26695: multidrug resistance protein (msbA)
Member of NCBI Protein Clusters CLSK872343(See COMBREX Page ) (See NCBI page)
NCBI Entrez GeneID 899618
UniProtKB accession
RefSeq Protein accession NP_207873.1 (PROVISIONAL)
Gene Symbol(s)
  • symbol: HP1082
  • locus tag: HP1082
Organism Helicobacter pylori 26695 (NCBI TaxID: 85962)
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Post a comment about this gene to appear on this page (info).
Source Predicted function(s)
NCBI Protein Cluster Prediction multidrug resistance protein
Prof. David Horn 3.6.3: acting on acid anhydrides, catalyzing transmembrane movement / (References: 20034383)
Prof. Vitkup 3.6.3.30 / Confidence:0.044 (References: 19935659, 16507154)
Functional Status blueblue (function predicted, no experimental evidence)
Source of prediction NCBI Protein Clusters info
BLASTP hits to experimentally validated proteins
green msbA from Escherichia coli str. K-12 substr. MG1655
(%_identity=30.84; E_val=3e-81; BitScore=297.0)

other hits with E-value < 1e-05
Share the same Pfam domain composition with the following experimentally validated proteins
green yheH from Bacillus subtilis subsp. subtilis str. 168

to see the rest 9 genes click here
GO terms
  • MF: GO:0000166 : nucleotide binding : IEA
  • MF: GO:0005524 : ATP binding : IEA
  • MF: GO:0042626 : ATPase activity, coupled to transmembrane movement of substances : IEA
  • BP: GO:0006810 : transport : IEA
  • CC: GO:0016021 : integral to membrane : IEA
  • MF: GO:0017111 : nucleoside-triphosphatase activity : IEA
  • BP: GO:0055085 : transmembrane transport : IEA
  • MF: GO:0016887 : ATPase activity : IEA
Domain Structure from CDD
  • P-loop NTPase: P-loop containing Nucleoside Triphosphate Hydrolases. This domain family is found in bacteria and archaea, and is approx.... (More)
  • ABC_ATPase: ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involv.... (More)
  • MdlB: ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]
  • ABC_membrane: ABC transporter transmembrane region. putative transporter; Reviewed

See domain structure on NCBI Conserved Domain Database
Domain structure from Pfam
See domain structure on Pfam Database
The table at right lists genes that may be "functionally linked to" (i.e., participate in a common biological process, or form a protein complex with) the subject gene of this page, as determined by two sequence-independent methods, including phylogenetic profiling and operon membership (determined by OperonDB). (Info.) These linkages may also be viewed graphically using the program VisANT, by clicking on the headers of the table. Note: VisANT requires Java. To install the latest version of Java, see www.java.com
 OperonDB
HP1080hypothetical protein
 
HP1081hypothetical protein
 
HP1083hypothetical protein
 
pyrBaspartate carbamoyltransferase catalytic subunit