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Gene trmD from Helicobacter pylori 26695: tRNA (guanine-N(1)-)-methyltransferase
Member of NCBI Protein Clusters PRK00026(See COMBREX Page ) (See NCBI page)
NCBI Entrez GeneID 899686
UniProtKB accession
RefSeq Protein accession NP_207939.1 (PROVISIONAL)
Gene Symbol(s)
  • symbol: trmD
  • locus tag: HP1148
Organism Helicobacter pylori 26695 (NCBI TaxID: 85962)
Other Cross References:
  • S
    Structure(s) available in PDB:
  • C
    Gene cloned by a participant in the Protein Structure Initiative (PSI): TargetDB. (To obtain a clone, please contact the PSI:Biology-Materials Repository.)
  • U
    Protein purified by a participant in the Protein Structure Initiative (PSI): TargetDB. (If you are interested in collaborating to obtain the protein, please contact the Northeast Structural Genomics consortium).
  • Protein described in EcoCyc:
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Post a comment about this gene to appear on this page (info).
Source Predicted function(s)
NCBI Protein Cluster Prediction tRNA (guanine-N(1)-)-methyltransferase
Combrex_01 ortholog of E. coli trmD / Anton BP unpublished
Functional Status blueblue (function predicted, no experimental evidence)
Source of prediction NCBI Protein Clusters info
EC number
BLASTP hits to experimentally validated proteins This gene does not have a BLAST match to any experimentally validated gene with an E value below 1e-5
GO terms
  • MF: GO:0009019 : tRNA (guanine-N1-)-methyltransferase activity : IEA
  • CC: GO:0005737 : cytoplasm : IEA
  • BP: GO:0008033 : tRNA processing : IEA
  • MF: GO:0008168 : methyltransferase activity : IEA
  • BP: GO:0006400 : tRNA modification : IEA
  • MF: GO:0016740 : transferase activity : IEA
  • MF: GO:0003723 : RNA binding : IEA
Domain Structure from CDD
  • tRNA_m1G_MT: tRNA (Guanine-1)-methyltransferase. tRNA (guanine-N(1)-)-methyltransferase/unknown domain fusion protein; Provisional

See domain structure on NCBI Conserved Domain Database
Domain structure from Pfam
See domain structure on Pfam Database
The table at right lists genes that may be "functionally linked to" (i.e., participate in a common biological process, or form a protein complex with) the subject gene of this page, as determined by two sequence-independent methods, including phylogenetic profiling and operon membership (determined by OperonDB). (Info.) These linkages may also be viewed graphically using the program VisANT, by clicking on the headers of the table. Note: VisANT requires Java. To install the latest version of Java, see
gene neighbourhoods
phylogenetic profile
HP1146hypothetical protein
rplS50S ribosomal protein L19
HP1149hypothetical protein
HP1150hypothetical protein
rpmI50S ribosomal protein L35  
secApreprotein translocase subunit SecA  
HP1448ribonuclease P, protein component (rnpA)  
ruvAHolliday junction DNA helicase RuvA  
rpsT30S ribosomal protein S20  
HP1362replicative DNA helicase  
HP0717DNA polymerase III subunits gamma and tau  
HP0955prolipoprotein diacylglyceryl transferase  
ruvBHolliday junction DNA helicase RuvB  
rplU50S ribosomal protein L21  
tsfelongation factor Ts  
infCtranslation initiation factor IF-3  
smpBSsrA-binding protein  
dnaAchromosomal replication initiation protein  
rpmE50S ribosomal protein L31  
lspAlipoprotein signal peptidase  
rplT50S ribosomal protein L20  
tigtrigger factor  
defpeptide deformylase  
HP1051hypothetical protein  
ligANAD-dependent DNA ligase LigA  
mraWS-adenosyl-methyltransferase MraW  
HP1247DNA polymerase III subunit delta  
HP0088RNA polymerase sigma factor RpoD  
rbfAribosome-binding factor A  
secEpreprotein translocase membrane subunit  
nusBtranscription antitermination protein NusB  
dnaEDNA polymerase III subunit alpha  
rplI50S ribosomal protein L9