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Gene pdxA from Helicobacter pylori 26695: 4-hydroxythreonine-4-phosphate dehydrogenase
Member of NCBI Protein Clusters PRK03946(See COMBREX Page ) (See NCBI page)
NCBI Entrez GeneID 899708
UniProtKB accession
RefSeq Protein accession NP_208374.1 (PROVISIONAL)
Gene Symbol(s)
  • symbol: pdxA
  • locus tag: HP1583
Organism Helicobacter pylori 26695 (NCBI TaxID: 85962)
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Source Predicted function(s)
NCBI Protein Cluster Prediction 4-hydroxythreonine-4-phosphate dehydrogenase
Prof. Vitkup / Confidence:0.966 (References: 19935659, 16507154)
Functional Status blueblue (function predicted, no experimental evidence)
Source of prediction NCBI Protein Clusters info
EC number
BLASTP hits to experimentally validated proteins
green pdxA from Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
(%_identity=33.33; E_val=9e-37; BitScore=149.0)

other hits with E-value < 1e-05
Share the same Pfam domain composition with the following experimentally validated proteins
green pdxA from Escherichia coli str. K-12 substr. MG1655

to see the rest 4 genes click here
GO terms
  • BP: GO:0055114 : oxidation reduction : IEA
  • CC: GO:0005737 : cytoplasm : IEA
  • MF: GO:0046872 : metal ion binding : IEA
  • MF: GO:0051287 : NAD or NADH binding : IEA
  • BP: GO:0008615 : pyridoxine biosynthetic process : IEA
  • BP: GO:0042823 : pyridoxal phosphate biosynthetic process : IEA
  • MF: GO:0016491 : oxidoreductase activity : IEA
  • MF: GO:0050570 : 4-hydroxythreonine-4-phosphate dehydrogenase activity : IEA
Domain Structure from CDD
  • PdxA: Pyridoxal phosphate biosynthetic protein PdxA. 4-hydroxythreonine-4-phosphate dehydrogenase; Provisional
  • pdxA: 4-hydroxythreonine-4-phosphate dehydrogenase; Reviewed

See domain structure on NCBI Conserved Domain Database
Domain structure from Pfam
See domain structure on Pfam Database
The table at right lists genes that may be "functionally linked to" (i.e., participate in a common biological process, or form a protein complex with) the subject gene of this page, as determined by two sequence-independent methods, including phylogenetic profiling and operon membership (determined by OperonDB). (Info.) These linkages may also be viewed graphically using the program VisANT, by clicking on the headers of the table. Note: VisANT requires Java. To install the latest version of Java, see
phylogenetic profile
flgGflagellar basal body rod protein FlgG
HP1584putative DNA-binding/iron metalloprotein/AP endonu
HP1582pyridoxine 5'-phosphate synthase
HP0582hypothetical protein 
HP0916iron-regulated outer membrane protein (frpB) 
HP1511hypothetical protein 
HP0605hypothetical protein 
HP0915iron-regulated outer membrane protein (frpB) 
HP1341siderophore-mediated iron transport protein (tonB) 
HP1512iron-regulated outer membrane protein (frpB) 
HP0876iron-regulated outer membrane protein (frpB) 
HP1489lipase-like protein