Gene HP1478 from Helicobacter pylori 26695: DNA helicase II (uvrD)
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Member of NCBI Protein Clusters
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CLSK872561(See COMBREX Page ) (See NCBI page)
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NCBI Entrez GeneID
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899814
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UniProtKB accession
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RefSeq Protein accession
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NP_208269.1 (PROVISIONAL)
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Gene Symbol(s)
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- symbol: HP1478
- locus tag: HP1478
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Organism
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Helicobacter pylori 26695 (NCBI TaxID: 85962)
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Initiate the grant application process for experimentally validating this gene (Important notice about COMBREX grants.)
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Contribute a predicted function for this gene (free text, GO terms, or EC number) (info). Be sure to
check the list of current predicted functions in the section immediately below beforehand.
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Nominate this gene for the Gold Standard Gene Database (if you believe it has been experimentally
validated) (info).
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Post a comment about this gene to appear on this page (info).
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Functional Status
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blue (function predicted, no experimental evidence)
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Source of prediction
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NCBI Protein Clusters info
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BLASTP hits to experimentally validated proteins
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other hits with E-value < 1e-05
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Share the same Pfam domain composition with the following experimentally validated proteins
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to see the rest 12 genes click here
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GO terms
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MF:
GO:0000166 : nucleotide binding : IEA
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MF:
GO:0005524 : ATP binding : IEA
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BP:
GO:0006281 : DNA repair : IEA
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MF:
GO:0004003 : ATP-dependent DNA helicase activity : IEA
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MF:
GO:0003677 : DNA binding : IEA
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MF:
GO:0004386 : helicase activity : IEA
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MF:
GO:0016787 : hydrolase activity : IEA
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Domain Structure from CDD
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- UvrD: Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]
- UvrD-helicase: UvrD/REP helicase. exonuclease V subunit beta; Provisional
- DUF699: Putative ATPase (DUF699). exonuclease V subunit alpha; Provisional
See domain structure on NCBI Conserved Domain Database
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Domain structure from Pfam
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See domain structure on Pfam Database
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The table at right lists genes that may be "functionally linked to" (i.e., participate in a common biological process, or form a protein complex with) the subject gene of this page,
as determined by two sequence-independent methods, including phylogenetic profiling and operon membership (determined by OperonDB).
(Info.)
These linkages may also be viewed graphically using the program VisANT, by clicking on the headers of the table.
Note: VisANT requires Java. To install the latest version of Java, see www.java.com
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| | HP1480 | seryl-tRNA synthetase | | | | HP1479 | hypothetical protein | | | | HP1476 | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase | | | | flgA | flagellar basal body P-ring biosynthesis protein F | | | | HP0110 | co-chaperone and heat shock protein (grpE) | | |
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| Phenotype |
Description |
Expression
Class |
Reference(s) |
| Candidate essential gene |
Identified as essential gene in one or more studies (see references) |
Knock out |
(candidate essential)
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