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Gene HP1446 from Helicobacter pylori 26695: biopolymer transport protein (exbD)
Member of NCBI Protein Clusters CLSK496495(See COMBREX Page ) (See NCBI page)
NCBI Entrez GeneID 899848
UniProtKB accession
RefSeq Protein accession NP_208237.1 (PROVISIONAL)
Gene Symbol(s)
  • symbol: HP1446
  • locus tag: HP1446
Organism Helicobacter pylori 26695 (NCBI TaxID: 85962)
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Source Predicted function(s)
NCBI Protein Cluster Prediction biopolymer transport protein
Berkeley Phylogenomics Group GO:0005515 protein binding / (References: 19435885)
Functional Status blueblue (function predicted, no experimental evidence)
Source of prediction NCBI Protein Clusters info
BLASTP hits to experimentally validated proteins
green exbD from Haemophilus influenzae Rd KW20
(%_identity=34.68; E_val=4e-17; BitScore=81.6)

other hits with E-value < 1e-05
Share the same Pfam domain composition with the following experimentally validated proteins
green exbD from Pseudomonas putida

to see the rest 5 genes click here
GO terms
  • MF: GO:0005215 : transporter activity : IEA
  • CC: GO:0016020 : membrane : IEA
  • BP: GO:0015031 : protein transport : IEA
  • BP: GO:0006810 : transport : IEA
  • CC: GO:0005886 : plasma membrane : IEA
  • CC: GO:0016021 : integral to membrane : IEA
Domain Structure from CDD
  • ExbD: Biopolymer transport protein ExbD/TolR. biopolymer transport protein ExbD; Provisional

See domain structure on NCBI Conserved Domain Database
Domain structure from Pfam
See domain structure on Pfam Database
The table at right lists genes that may be "functionally linked to" (i.e., participate in a common biological process, or form a protein complex with) the subject gene of this page, as determined by two sequence-independent methods, including phylogenetic profiling and operon membership (determined by OperonDB). (Info.) These linkages may also be viewed graphically using the program VisANT, by clicking on the headers of the table. Note: VisANT requires Java. To install the latest version of Java, see
 gene neighbourhoods
phylogenetic profile
HP1445biopolymer transport protein (exbB)
HP1448ribonuclease P, protein component (rnpA) 
rpmH50S ribosomal protein L34 
smpBSsrA-binding protein 
HP1489lipase-like protein  
HP09573-deoxy-D-manno-octulosonic-acid transferase  
HP0915iron-regulated outer membrane protein (frpB)  
HP00032-dehydro-3-deoxyphosphooctonate aldolase  
HP1375UDP-N-acetylglucosamine acyltransferase  
HP0605hypothetical protein  
lpxKtetraacyldisaccharide 4'-kinase  
HP0582hypothetical protein  
HP1130biopolymer transport protein (exbB)  
lpxDUDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltra  
lpxCUDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine d  
HP1511hypothetical protein  
HP1341siderophore-mediated iron transport protein (tonB)  
HP0876iron-regulated outer membrane protein (frpB)  
HP0916iron-regulated outer membrane protein (frpB)  
HP02303-deoxy-manno-octulosonate cytidylyltransferase  
HP0655protective surface antigen D15  
HP1512iron-regulated outer membrane protein (frpB)  
lpxBipid-A-disaccharide synthase  
HP1339biopolymer transport protein (exbB)  
Phenotype Description Expression
Candidate essential gene Identified as essential gene in one or more studies (see references) Knock out
PMID: 15547264
(candidate essential)