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Gene valS from Helicobacter pylori 26695: valyl-tRNA synthetase
Member of NCBI Protein Clusters PRK05729(See COMBREX Page ) (See NCBI page)
NCBI Entrez GeneID 899913
UniProtKB accession
RefSeq Protein accession NP_207944.1 (PROVISIONAL)
Gene Symbol(s)
  • symbol: valS
  • locus tag: HP1153
Organism Helicobacter pylori 26695 (NCBI TaxID: 85962)
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Source Predicted function(s)
NCBI Protein Cluster Prediction valyl-tRNA synthetase
Prof. Vitkup / Confidence:0.691 (References: 19935659, 16507154)
Berkeley Phylogenomics Group GO:0045174 glutathione dehydrogenase (ascorbate) activity / (References: 19435885)
Berkeley Phylogenomics Group GO:0004823 leucine-tRNA ligase activity / (References: 19435885)
Berkeley Phylogenomics Group GO:0042802 identical protein binding / (References: 19435885)
Berkeley Phylogenomics Group GO:0005515 protein binding / (References: 19435885)
Berkeley Phylogenomics Group GO:0004822 isoleucine-tRNA ligase activity / (References: 19435885)
Berkeley Phylogenomics Group Valine--tRNA ligase. / (References: 19435885)
Berkeley Phylogenomics Group Isoleucine--tRNA ligase. / (References: 19435885)
Berkeley Phylogenomics Group GO:0004832 valine-tRNA ligase activity / (References: 19435885)
Functional Status blueblue (function predicted, no experimental evidence)
Source of prediction NCBI Protein Clusters info
EC number
BLASTP hits to experimentally validated proteins
green valS from Geobacillus stearothermophilus
(%_identity=41.23; E_val=0.0; BitScore=685.0)

other hits with E-value < 1e-05
Share the same Pfam domain composition with the following experimentally validated proteins
green valS from Geobacillus stearothermophilus

to see the rest 4 genes click here
GO terms
  • MF: GO:0005524 : ATP binding : IEA
  • MF: GO:0004832 : valine-tRNA ligase activity : IEA
  • MF: GO:0016874 : ligase activity : IEA
  • BP: GO:0006412 : translation : IEA
  • BP: GO:0006438 : valyl-tRNA aminoacylation : IEA
  • BP: GO:0006418 : tRNA aminoacylation for protein translation : IEA
  • MF: GO:0000166 : nucleotide binding : IEA
  • CC: GO:0005737 : cytoplasm : IEA
  • MF: GO:0004812 : aminoacyl-tRNA ligase activity : IEA
Domain Structure from CDD
  • valS: valyl-tRNA synthetase; Reviewed
  • Anticodon_Ia_Val: Anticodon-binding domain of valyl tRNA synthetases. This domain is found in valyl tRNA synthetases (ValRS), which belong.... (More)
  • nt_trans: nucleotidyl transferase superfamily. CTP:phosphocholine cytidylyltransferase (CCT) catalyzes the condensation of CTP and.... (More)
  • ValRS_core: catalytic core domain of valyl-tRNA synthetases. This is the catalytic core domain of valine amino-acyl tRNA synthetases.... (More)
  • nt_trans: nucleotidyl transferase superfamily. nt_trans (nucleotidyl transferase) This superfamily includes the class I amino-acyl.... (More)

See domain structure on NCBI Conserved Domain Database
Domain structure from Pfam
See domain structure on Pfam Database
The table at right lists genes that may be "functionally linked to" (i.e., participate in a common biological process, or form a protein complex with) the subject gene of this page, as determined by two sequence-independent methods, including phylogenetic profiling and operon membership (determined by OperonDB). (Info.) These linkages may also be viewed graphically using the program VisANT, by clicking on the headers of the table. Note: VisANT requires Java. To install the latest version of Java, see
rpsP30S ribosomal protein S16
HP1152signal recognition particle protein (ffh)
Phenotype Description Expression
Candidate essential gene Identified as essential gene in one or more studies (see references) Knock out
PMID: 15547264
(candidate essential)