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Gene HP1198 from Helicobacter pylori 26695: DNA-directed RNA polymerase subunit beta/beta'
Member of NCBI Protein Clusters PRK09603(See COMBREX Page ) (See NCBI page)
NCBI Entrez GeneID 899960
UniProtKB accession
RefSeq Protein accession NP_207989.1 (PROVISIONAL)
Gene Symbol(s)
  • symbol: HP1198
  • locus tag: HP1198
Organism Helicobacter pylori 26695 (NCBI TaxID: 85962)
Other Cross References:
  • S
    Structure(s) available in PDB:
  • C
    Gene cloned by a participant in the Protein Structure Initiative (PSI): TargetDB. (To obtain a clone, please contact the PSI:Biology-Materials Repository.)
  • U
    Protein purified by a participant in the Protein Structure Initiative (PSI): TargetDB. (If you are interested in collaborating to obtain the protein, please contact the Northeast Structural Genomics consortium).
  • Protein described in EcoCyc:
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Contribute a predicted function for this gene (free text, GO terms, or EC number) (info). Be sure to check the list of current predicted functions in the section immediately below beforehand.
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Post a comment about this gene to appear on this page (info).
Source Predicted function(s)
NCBI Protein Cluster Prediction DNA-directed RNA polymerase subunit beta/beta'
Prof. David Horn 2.7.7.6: DNA-directed RNA polymerase / (References: 20034383)
Berkeley Phylogenomics Group GO:0031625 ubiquitin protein ligase binding / (References: 19435885)
Berkeley Phylogenomics Group 2.7.7.6: DNA-directed RNA polymerase. / (References: 19435885)
Berkeley Phylogenomics Group GO:0005515 protein binding / (References: 19435885)
Berkeley Phylogenomics Group GO:0003677 DNA binding / (References: 19435885)
Source References Functional description
GSDB
[PMID: 9677352]
Bifunctional DNA-directed RNA polymerase subunit beta-beta' (source organism: Helicobacter pylori (Campylobacter pylori).; strain specific ID: DSM 4867 / CCUG 17874 / NCTC 11638, HP1, J-116, and SS1)
Functional Status greenGreen (experimental evidence, uncurated)
EC number 2.7.7.6 (See reaction via BRENDA)) (Source: BRENDA)
GO terms
  • MF: GO:0003824 : catalytic activity : IEA
  • BP: GO:0006351 : transcription, DNA-dependent : IEA
  • MF: GO:0003899 : DNA-directed RNA polymerase activity : IEA
  • BP: GO:0006350 : transcription : IEA
  • MF: GO:0003677 : DNA binding : IEA
  • MF: GO:0016779 : nucleotidyltransferase activity : IEA
  • MF: GO:0016740 : transferase activity : IEA
Domain Structure from CDD
  • RNA_pol_B_RPB2: RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a sin.... (More)
  • RNA_pol_Rpb1_1: RNA polymerase Rpb1, domain 1. RNA polymerases catalyse the DNA dependent polymerisation of RNA. Prokaryotes contain a s.... (More)
  • RNAP_largest_subunit_C: Largest subunit of RNA polymerase (RNAP), C-terminal domain. RNA polymerase (RNAP) is a large multi-subunit complex resp.... (More)
  • RNA_pol_Rpb1_3: RNA polymerase Rpb1, domain 3. RNA polymerases catalyse the DNA dependent polymerisation of RNA. Prokaryotes contain a s.... (More)
  • RNA_pol_Rpb2_1: RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerisation of RNA. Prokaryotes contain a sin.... (More)
  • RNAP_beta'_C: Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain. Bacterial RNA polymerase (R.... (More)
  • RNAP_largest_subunit_C: Largest subunit of RNA polymerase (RNAP), C-terminal domain. Archaeal RNA polymerase (RNAP), like bacterial RNAP, is a l.... (More)
  • RNA_pol_Rpb1_2: RNA polymerase Rpb1, domain 2. RNA polymerases catalyse the DNA dependent polymerisation of RNA. Prokaryotes contain a s.... (More)
  • RNA_pol_Rpb1_4: RNA polymerase Rpb1, domain 4. RNA polymerases catalyse the DNA dependent polymerisation of RNA. Prokaryotes contain a s.... (More)
  • RNA_pol_B_RPB2: N/A. RNA polymerases catalyse the DNA dependent polymerisation of RNA. Prokaryotes contain a single RNA polymerase compa.... (More)
  • PRK09603: DNA-directed RNA polymerase subunit beta/beta'; Reviewed

See domain structure on NCBI Conserved Domain Database
Domain structure from Pfam
See domain structure on Pfam Database
Based on the function of this gene, COMBREX predictions were made to the following related genes (mouse over gene symbol for details) [Download ]
HPAG1_1137 , HPG27_1142 , HPSH_06195 , rpoB (3)
The table at right lists genes that may be "functionally linked to" (i.e., participate in a common biological process, or form a protein complex with) the subject gene of this page, as determined by two sequence-independent methods, including phylogenetic profiling and operon membership (determined by OperonDB). (Info.) These linkages may also be viewed graphically using the program VisANT, by clicking on the headers of the table. Note: VisANT requires Java. To install the latest version of Java, see www.java.com
 OperonDB
gene neighbourhoods
HP119630S ribosomal protein S7
 
 
rpsL30S ribosomal protein S12
 
 
rplL50S ribosomal protein L7/L12
 
 
rplJ50S ribosomal protein L10