Gene nusG from Helicobacter pylori 26695: transcription antitermination protein NusG
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Member of NCBI Protein Clusters
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PRK05609(See COMBREX Page ) (See NCBI page)
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NCBI Entrez GeneID
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899966
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UniProtKB accession
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RefSeq Protein accession
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NP_207994.1 (PROVISIONAL)
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Gene Symbol(s)
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- symbol: nusG
- locus tag: HP1203
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Organism
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Helicobacter pylori 26695 (NCBI TaxID: 85962)
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Initiate the grant application process for experimentally validating this gene (Important notice about COMBREX grants.)
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Contribute a predicted function for this gene (free text, GO terms, or EC number) (info). Be sure to
check the list of current predicted functions in the section immediately below beforehand.
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Nominate this gene for the Gold Standard Gene Database (if you believe it has been experimentally
validated) (info).
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Post a comment about this gene to appear on this page (info).
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Functional Status
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blue (function predicted, no experimental evidence)
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Source of prediction
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NCBI Protein Clusters info
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BLASTP hits to experimentally validated proteins
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other hits with E-value < 1e-05
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Share the same Pfam domain composition with the following experimentally validated proteins
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to see the rest 2 gene click here
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GO terms
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BP:
GO:0032968 : positive regulation of RNA elongation from RNA polymerase II promoter : IEA
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MF:
GO:0003711 : transcription elongation regulator activity : IEA
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BP:
GO:0006350 : transcription : IEA
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BP:
GO:0031564 : transcription antitermination : IEA
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BP:
GO:0045449 : regulation of transcription : IEA
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BP:
GO:0006355 : regulation of transcription, DNA-dependent : IEA
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BP:
GO:0006353 : transcription termination : IEA
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Domain Structure from CDD
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- NusG: Transcription termination factor nusG. Spt5p and prokaryotic NusG are shown to contain a novel 'NGN' domain. The combined NGN and KOW motif regions of Spt5 form the binding domain with Spt4. Spt5 complexes with Spt4 as a 1:1 heterodimer snf this Spt5-Spt4 complex regulates early transcription elongation by RNA polymerase II and has an imputed role in pre-mRNA processing via its physical association with mRNA capping enzymes. The Schizosaccharomyces pombe core Spt5-Spt4 complex is a heterodimer bearing a trypsin-resistant Spt4-binding domain within the Spt5 subunit..... (More)
- nusG: transcription antitermination protein NusG; Validated
See domain structure on NCBI Conserved Domain Database
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Domain structure from Pfam
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See domain structure on Pfam Database
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The table at right lists genes that may be "functionally linked to" (i.e., participate in a common biological process, or form a protein complex with) the subject gene of this page,
as determined by two sequence-independent methods, including phylogenetic profiling and operon membership (determined by OperonDB).
(Info.)
These linkages may also be viewed graphically using the program VisANT, by clicking on the headers of the table.
Note: VisANT requires Java. To install the latest version of Java, see www.java.com
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| | rpmG | 50S ribosomal protein L33 | | | | secE | preprotein translocase subunit SecE | | | | rplA | 50S ribosomal protein L1 | | | | rplK | 50S ribosomal protein L11 | | |
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| Phenotype |
Description |
Expression
Class |
Reference(s) |
| Candidate essential gene |
Identified as essential gene in one or more studies (see references) |
Knock out |
(candidate essential)
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