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Gene prfA from Helicobacter pylori 26695: peptide chain release factor 1
Member of NCBI Protein Clusters PRK00591(See COMBREX Page ) (See NCBI page)
NCBI Entrez GeneID 899973
UniProtKB accession
RefSeq Protein accession NP_206877.1 (PROVISIONAL)
Gene Symbol(s)
  • symbol: prfA
  • locus tag: HP0077
Organism Helicobacter pylori 26695 (NCBI TaxID: 85962)
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Source Predicted function(s)
NCBI Protein Cluster Prediction peptide chain release factor 1
Berkeley Phylogenomics Group GO:0005515 protein binding / (References: 19435885)
Functional Status blueblue (function predicted, no experimental evidence)
Source of prediction NCBI Protein Clusters info
BLASTP hits to experimentally validated proteins
green prfA from Escherichia coli str. K-12 substr. MG1655
(%_identity=53.58; E_val=1e-107; BitScore=384.0)

other hits with E-value < 1e-05
Share the same Pfam domain composition with the following experimentally validated proteins
green prfA from Escherichia coli str. K-12 substr. MG1655

to see the rest 3 genes click here
GO terms
  • CC: GO:0005737 : cytoplasm : IEA
  • MF: GO:0003747 : translation release factor activity : IEA
  • MF: GO:0016149 : translation release factor activity, codon specific : IEA
  • BP: GO:0006412 : translation : IEA
  • BP: GO:0006415 : translational termination : IEA
Domain Structure from CDD
  • RF-1: RF-1 domain. peptidyl-tRNA hydrolase domain protein; Provisional
  • prfA: peptide chain release factor 1; Validated

See domain structure on NCBI Conserved Domain Database
Domain structure from Pfam
See domain structure on Pfam Database
The table at right lists genes that may be "functionally linked to" (i.e., participate in a common biological process, or form a protein complex with) the subject gene of this page, as determined by two sequence-independent methods, including phylogenetic profiling and operon membership (determined by OperonDB). (Info.) These linkages may also be viewed graphically using the program VisANT, by clicking on the headers of the table. Note: VisANT requires Java. To install the latest version of Java, see
phylogenetic profile
HP0078hypothetical protein
rpsT30S ribosomal protein S20
HP0079outer membrane protein (omp3)
HP1497peptidyl-tRNA hydrolase 
rpmI50S ribosomal protein L35 
rplI50S ribosomal protein L9 
tufelongation factor Tu 
HP0013hypothetical protein 
mnmAtRNA-specific 2-thiouridylase MnmA 
rpsP30S ribosomal protein S16 
HP0286cell division protein (ftsH) 
fmtmethionyl-tRNA formyltransferase 
rpsF30S ribosomal protein S6 
HP0559acyl carrier protein (acpP) 
tsfelongation factor Ts 
aspSaspartyl-tRNA synthetase 
rplQ50S ribosomal protein L17 
HP0745hypothetical protein 
HP0962acyl carrier protein (acpP) 
rncribonuclease III 
rplS50S ribosomal protein L19 
HP1069cell division protein (ftsH) 
rpsR30S ribosomal protein S18 
rplL50S ribosomal protein L7/L12 
HP0347hypothetical protein 
rpmA50S ribosomal protein L27 
HP1450putative inner membrane protein translocase compon 
rpmG50S ribosomal protein L33 
frrribosome recycling factor 
HP0355GTP-binding protein LepA 
HP1245single-stranded DNA-binding protein 
HP0956hypothetical protein 
obgEGTPase ObgE