Combrex Enter Keyword, gene symbol, or identifier (more options; Help )
Enter species name
Gene functional status (select)
Phenotype association (select)[View list of phenotypes]
Check to restrict search to:
Genes in Category A-C and Emerging/Re-Emerging pathogens
Genes in curated Protein Clusters
Genes with predictions submitted to COMBREX
P
Genes with solved structures in PDB
S
Genes with Pfam domains shared with human proteins
H
Genes with products purified by PSI
U
Genes cloned by PSI
C
close options

 

Gene HP0103 from Helicobacter pylori 26695: methyl-accepting chemotaxis protein (tlpB)
Member of NCBI Protein Clusters CLSK495862(See COMBREX Page ) (See NCBI page)
NCBI Entrez GeneID 900016
UniProtKB accession
RefSeq Protein accession NP_206903.1 (PROVISIONAL)
Gene Symbol(s)
  • symbol: HP0103
  • locus tag: HP0103
Organism Helicobacter pylori 26695 (NCBI TaxID: 85962)
Initiate the grant application process for experimentally validating this gene (Important notice about COMBREX grants.)
Contribute a predicted function for this gene (free text, GO terms, or EC number) (info). Be sure to check the list of current predicted functions in the section immediately below beforehand.
Nominate this gene for the Gold Standard Gene Database (if you believe it has been experimentally validated) (info).
Post a comment about this gene to appear on this page (info).
Source Predicted function(s)
NCBI Protein Cluster Prediction methyl-accepting chemotaxis protein
Berkeley Phylogenomics Group GO:0005515 protein binding / (References: 19435885)
Functional Status blueblue (function predicted, no experimental evidence)
Source of prediction NCBI Protein Clusters info
BLASTP hits to experimentally validated proteins This gene does not have a BLAST match to any experimentally validated gene with an E value below 1e-5
GO terms
  • CC: GO:0016020 : membrane : IEA
  • BP: GO:0006935 : chemotaxis : IEA
  • MF: GO:0004871 : signal transducer activity : IEA
  • BP: GO:0007165 : signal transduction : IEA
  • CC: GO:0016021 : integral to membrane : IEA
Domain Structure from CDD
  • HAMP: N/A. FOG: HAMP domain [Signal transduction mechanisms]
  • COG4564: Signal transduction histidine kinase [Signal transduction mechanisms]
  • MA: Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). Thought to undergo reversible methylation in r.... (More)
  • TarH: N/A. This domain is thought to transduce the signal to CheA since it is highly conserved in very diverse MCPs.

See domain structure on NCBI Conserved Domain Database
Domain structure from Pfam
See domain structure on Pfam Database
The table at right lists genes that may be "functionally linked to" (i.e., participate in a common biological process, or form a protein complex with) the subject gene of this page, as determined by two sequence-independent methods, including phylogenetic profiling and operon membership (determined by OperonDB). (Info.) These linkages may also be viewed graphically using the program VisANT, by clicking on the headers of the table. Note: VisANT requires Java. To install the latest version of Java, see www.java.com
 OperonDB
phylogenetic profile
HP01042',3'-cyclic-nucleotide 2'-phosphodiesterase (cpdB
 
 
HP0102hypothetical protein
 
 
HP0105S-ribosylhomocysteinase
 
 
HP0616chemotaxis protein (cheV) 
 
HP0391purine-binding chemotaxis protein (cheW) 
 
HP0019chemotaxis protein (cheV) 
 
HP0393chemotaxis protein (cheV) 
 
HP0392histidine kinase (cheA)