Combrex Enter Keyword, gene symbol, or identifier (more options; Help )
Enter species name
Gene functional status (select)
Phenotype association (select)[View list of phenotypes]
Check to restrict search to:
Genes in Category A-C and Emerging/Re-Emerging pathogens
Genes in curated Protein Clusters
Genes with predictions submitted to COMBREX
Genes with solved structures in PDB
Genes with Pfam domains shared with human proteins
Genes with products purified by PSI
Genes cloned by PSI
close options


Gene argS from Helicobacter pylori 26695: arginyl-tRNA synthetase
Member of NCBI Protein Clusters PRK01611(See COMBREX Page ) (See NCBI page)
NCBI Entrez GeneID 900101
UniProtKB accession
RefSeq Protein accession NP_207117.1 (PROVISIONAL)
Gene Symbol(s)
  • symbol: argS
  • locus tag: HP0319
Organism Helicobacter pylori 26695 (NCBI TaxID: 85962)
Initiate the grant application process for experimentally validating this gene (Important notice about COMBREX grants.)
Contribute a predicted function for this gene (free text, GO terms, or EC number) (info). Be sure to check the list of current predicted functions in the section immediately below beforehand.
Nominate this gene for the Gold Standard Gene Database (if you believe it has been experimentally validated) (info).
Post a comment about this gene to appear on this page (info).
Source Predicted function(s)
NCBI Protein Cluster Prediction arginyl-tRNA synthetase
Prof. Vitkup / Confidence:0.535 (References: 19935659, 16507154)
Berkeley Phylogenomics Group GO:0005524 ATP binding / (References: 19435885)
Berkeley Phylogenomics Group Arginine--tRNA ligase. / (References: 19435885)
Berkeley Phylogenomics Group GO:0000049 tRNA binding / (References: 19435885)
Berkeley Phylogenomics Group GO:0005515 protein binding / (References: 19435885)
Berkeley Phylogenomics Group GO:0004814 arginine-tRNA ligase activity / (References: 19435885)
Berkeley Phylogenomics Group GO:0034618 arginine binding / (References: 19435885)
Functional Status blueblue (function predicted, no experimental evidence)
Source of prediction NCBI Protein Clusters info
EC number
BLASTP hits to experimentally validated proteins This gene does not have a BLAST match to any experimentally validated gene with an E value below 1e-5
GO terms
  • MF: GO:0016874 : ligase activity : IEA
  • MF: GO:0005524 : ATP binding : IEA
  • BP: GO:0006412 : translation : IEA
  • BP: GO:0006420 : arginyl-tRNA aminoacylation : IEA
  • BP: GO:0006418 : tRNA aminoacylation for protein translation : IEA
  • MF: GO:0004814 : arginine-tRNA ligase activity : IEA
  • MF: GO:0000166 : nucleotide binding : IEA
  • CC: GO:0005737 : cytoplasm : IEA
  • MF: GO:0004812 : aminoacyl-tRNA ligase activity : IEA
Domain Structure from CDD
  • ArgRS_core: catalytic core domain of arginyl-tRNA synthetases. This is the catalytic core domain of Arginyl tRNA synthetase (ArgRS)..... (More)
  • Arg_tRNA_synt_N: Arginyl tRNA synthetase N terminal domain. This domain is found at the amino terminus of Arginyl tRNA synthetase, also c.... (More)
  • Anticodon_Ia_like: Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains. This domain is found in a variety o.... (More)
  • Anticodon_Ia_like: Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains. This domain is found in cysteinyl t.... (More)
  • argS: arginyl-tRNA synthetase. This model recognizes arginyl-tRNA synthetase in every completed genome to date. An interesting.... (More)

See domain structure on NCBI Conserved Domain Database
Domain structure from Pfam
See domain structure on Pfam Database
The table at right lists genes that may be "functionally linked to" (i.e., participate in a common biological process, or form a protein complex with) the subject gene of this page, as determined by two sequence-independent methods, including phylogenetic profiling and operon membership (determined by OperonDB). (Info.) These linkages may also be viewed graphically using the program VisANT, by clicking on the headers of the table. Note: VisANT requires Java. To install the latest version of Java, see
HP0320hypothetical protein
HP0317outer membrane protein (omp9)
HP0318hypothetical protein
gmkguanylate kinase