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Gene HP0298 from Helicobacter pylori 26695: dipeptide ABC transporter, periplasmic dipeptide-binding protein (dppA)
Member of NCBI Protein Clusters CLSK495977(See COMBREX Page ) (See NCBI page)
NCBI Entrez GeneID 900107
UniProtKB accession
RefSeq Protein accession NP_207096.1 (PROVISIONAL)
Gene Symbol(s)
  • symbol: HP0298
  • locus tag: HP0298
Organism Helicobacter pylori 26695 (NCBI TaxID: 85962)
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Contribute a predicted function for this gene (free text, GO terms, or EC number) (info). Be sure to check the list of current predicted functions in the section immediately below beforehand.
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Post a comment about this gene to appear on this page (info).
Source Predicted function(s)
NCBI Protein Cluster Prediction periplasmic dipeptide-binding protein
Berkeley Phylogenomics Group GO:0016563 transcription activator activity / (References: 19435885)
Berkeley Phylogenomics Group GO:0005515 protein binding / (References: 19435885)
Berkeley Phylogenomics Group GO:0016151 nickel ion binding / (References: 19435885)
Berkeley Phylogenomics Group GO:0020037 heme binding / (References: 19435885)
Berkeley Phylogenomics Group GO:0042277 peptide binding / (References: 19435885)
Berkeley Phylogenomics Group GO:0016564 transcription repressor activity / (References: 19435885)
Berkeley Phylogenomics Group GO:0042936 dipeptide transporter activity / (References: 19435885)
Functional Status blueblue (function predicted, no experimental evidence)
Source of prediction NCBI Protein Clusters info
BLASTP hits to experimentally validated proteins
green dppA from Haemophilus influenzae Rd KW20
(%_identity=39.01; E_val=4e-109; BitScore=390.0)

other hits with E-value < 1e-05
Share the same Pfam domain composition with the following experimentally validated proteins
green gsiB from Escherichia coli str. K-12 substr. MG1655

to see the rest 16 genes click here
GO terms
  • BP: GO:0006810 : transport : IEA
  • MF: GO:0005215 : transporter activity : IEA
Domain Structure from CDD
  • PBP2_DppA_like: The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold. Thi.... (More)
  • SBP_bac_5: Bacterial extracellular solute-binding proteins, family 5 Middle. The borders of this family are based on the PDBSum def.... (More)

See domain structure on NCBI Conserved Domain Database
Domain structure from Pfam
See domain structure on Pfam Database
The table at right lists genes that may be "functionally linked to" (i.e., participate in a common biological process, or form a protein complex with) the subject gene of this page, as determined by two sequence-independent methods, including phylogenetic profiling and operon membership (determined by OperonDB). (Info.) These linkages may also be viewed graphically using the program VisANT, by clicking on the headers of the table. Note: VisANT requires Java. To install the latest version of Java, see
gene neighbourhoods
HP0299dipeptide ABC transporter, permease protein (dppB)
HP0300dipeptide ABC transporter, permease protein (dppC)
rplU50S ribosomal protein L21
rpmA50S ribosomal protein L27
Phenotype Description Expression
Candidate essential gene Identified as essential gene in one or more studies (see references) Knock out
PMID: 15547264
(candidate essential)