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Gene HP0306 from Helicobacter pylori 26695: glutamate-1-semialdehyde aminotransferase
Member of NCBI Protein Clusters PRK00062(See COMBREX Page ) (See NCBI page)
NCBI Entrez GeneID 900188
UniProtKB accession
RefSeq Protein accession NP_207104.1 (PROVISIONAL)
Gene Symbol(s)
  • symbol: HP0306
  • locus tag: HP0306
Organism Helicobacter pylori 26695 (NCBI TaxID: 85962)
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Source Predicted function(s)
NCBI Protein Cluster Prediction glutamate-1-semialdehyde aminotransferase
Prof. Vitkup / Confidence:0.974 (References: 19935659, 16507154)
Functional Status blueblue (function predicted, no experimental evidence)
Source of prediction NCBI Protein Clusters info
EC number
BLASTP hits to experimentally validated proteins
green hemL from Escherichia coli str. K-12 substr. MG1655
(%_identity=50.94; E_val=7e-125; BitScore=442.0)

other hits with E-value < 1e-05
Share the same Pfam domain composition with the following experimentally validated proteins
green bioA from Bacillus subtilis subsp. subtilis str. 168

to see the rest 24 genes click here
GO terms
  • MF: GO:0042286 : glutamate-1-semialdehyde 2,1-aminomutase activity : IEA
  • CC: GO:0005737 : cytoplasm : IEA
  • MF: GO:0003824 : catalytic activity : IEA
  • MF: GO:0008483 : transaminase activity : IEA
  • MF: GO:0016853 : isomerase activity : IEA
  • BP: GO:0006779 : porphyrin biosynthetic process : IEA
  • BP: GO:0033014 : tetrapyrrole biosynthetic process : IEA
  • MF: GO:0030170 : pyridoxal phosphate binding : IEA
Domain Structure from CDD
  • OAT_like: Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotran.... (More)
  • PRK00062: glutamate-1-semialdehyde aminotransferase; Provisional

See domain structure on NCBI Conserved Domain Database
Domain structure from Pfam
See domain structure on Pfam Database
The table at right lists genes that may be "functionally linked to" (i.e., participate in a common biological process, or form a protein complex with) the subject gene of this page, as determined by two sequence-independent methods, including phylogenetic profiling and operon membership (determined by OperonDB). (Info.) These linkages may also be viewed graphically using the program VisANT, by clicking on the headers of the table. Note: VisANT requires Java. To install the latest version of Java, see
domain fusion
HP0307hypothetical protein
HP0308hypothetical protein
HP0304hypothetical protein
HP0305hypothetical protein
HP0090acyl-carrier-protein S-malonyltransferase 
HP05583-oxoacyl-(acyl carrier protein) synthase II 
Metabolic Annotation from Palsson Lab

Metabolic Reaction: G1SATi

glutamate-1-semialdehyde aminotransferase
glu1sa[c] -> 5aop[c]
Heme biosynthesis

Source: Ported to COMBREX by Segre's Lab