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Gene HP0401 from Helicobacter pylori 26695: 3-phosphoshikimate 1-carboxyvinyltransferase
Member of NCBI Protein Clusters PRK02427(See COMBREX Page ) (See NCBI page)
NCBI Entrez GeneID 900233
UniProtKB accession
RefSeq Protein accession NP_207199.1 (PROVISIONAL)
Gene Symbol(s)
  • symbol: HP0401
  • locus tag: HP0401
Organism Helicobacter pylori 26695 (NCBI TaxID: 85962)
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Contribute a predicted function for this gene (free text, GO terms, or EC number) (info). Be sure to check the list of current predicted functions in the section immediately below beforehand.
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Source Predicted function(s)
NCBI Protein Cluster Prediction 3-phosphoshikimate 1-carboxyvinyltransferase
Prof. Vitkup / Confidence:0.931 (References: 19935659, 16507154)
Berkeley Phylogenomics Group 3-phosphoshikimate 1-carboxyvinyltransferase. / (References: 19435885)
Berkeley Phylogenomics Group GO:0004764 shikimate 5-dehydrogenase activity / (References: 19435885)
Berkeley Phylogenomics Group GO:0003866 3-phosphoshikimate 1-carboxyvinyltransferase activity / (References: 19435885)
Berkeley Phylogenomics Group GO:0004765 shikimate kinase activity / (References: 19435885)
Berkeley Phylogenomics Group GO:0003856 3-dehydroquinate synthase activity / (References: 19435885)
Berkeley Phylogenomics Group GO:0003855 3-dehydroquinate dehydratase activity / (References: 19435885)
Functional Status blueblue (function predicted, no experimental evidence)
Source of prediction NCBI Protein Clusters info
EC number
BLASTP hits to experimentally validated proteins
green aroE from Bacillus subtilis subsp. subtilis str. 168
(%_identity=39.57; E_val=3e-79; BitScore=290.0)

other hits with E-value < 1e-05
Share the same Pfam domain composition with the following experimentally validated proteins
green murA from Enterobacter cloacae subsp. cloacae ATCC 13047

to see the rest 7 genes click here
GO terms
  • MF: GO:0003824 : catalytic activity : IEA
  • CC: GO:0005737 : cytoplasm : IEA
  • MF: GO:0003866 : 3-phosphoshikimate 1-carboxyvinyltransferase activity : IEA
  • BP: GO:0008652 : cellular amino acid biosynthetic process : IEA
  • BP: GO:0009073 : aromatic amino acid family biosynthetic process : IEA
  • MF: GO:0016765 : transferase activity, transferring alkyl or aryl (other than methyl) groups : IEA
  • MF: GO:0016740 : transferase activity : IEA
Domain Structure from CDD
  • PRK02427: 3-phosphoshikimate 1-carboxyvinyltransferase; Provisional
  • EPSP_synthase: EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvylshikimate-3-phosphate synthase) (EC 2.5.... (More)

See domain structure on NCBI Conserved Domain Database
Domain structure from Pfam
See domain structure on Pfam Database
The table at right lists genes that may be "functionally linked to" (i.e., participate in a common biological process, or form a protein complex with) the subject gene of this page, as determined by two sequence-independent methods, including phylogenetic profiling and operon membership (determined by OperonDB). (Info.) These linkages may also be viewed graphically using the program VisANT, by clicking on the headers of the table. Note: VisANT requires Java. To install the latest version of Java, see
phylogenetic profile
domain fusion
pheTphenylalanyl-tRNA synthetase subunit beta
pheSphenylalanyl-tRNA synthetase subunit alpha
rpsA30S ribosomal protein S1
ispH4-hydroxy-3-methylbut-2-enyl diphosphate reductase
aroEshikimate 5-dehydrogenase 
HP0663chorismate synthase 
aroB3-dehydroquinate synthase  
Metabolic Annotation from Palsson Lab

Metabolic Reaction: PSCVT

3-phosphoshikimate 1-carboxyvinyltransferase
pep[c] + skm5p[c] <=> 3psme[c] + pi[c]
Chorismate Biosynthesis

Source: Ported to COMBREX by Segre's Lab