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Gene HP1260 from Helicobacter pylori 26695: NADH dehydrogenase subunit A
Member of NCBI Protein Clusters PRK08489(See COMBREX Page ) (See NCBI page)
NCBI Entrez GeneID 900263
UniProtKB accession
RefSeq Protein accession NP_208052.1 (PROVISIONAL)
Gene Symbol(s)
  • symbol: HP1260
  • locus tag: HP1260
Organism Helicobacter pylori 26695 (NCBI TaxID: 85962)
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Source Predicted function(s)
NCBI Protein Cluster Prediction NADH dehydrogenase subunit A
Prof. Vitkup / Confidence:0.504 (References: 19935659, 16507154)
Functional Status blueblue (function predicted, no experimental evidence)
Source of prediction NCBI Protein Clusters info
EC number
BLASTP hits to experimentally validated proteins This gene does not have a BLAST match to any experimentally validated gene with an E value below 1e-5
Share the same Pfam domain composition with the following experimentally validated proteins
green nuoA from Rhodobacter capsulatus

to see the rest 4 genes click here
GO terms
  • CC: GO:0016020 : membrane : IEA
  • BP: GO:0055114 : oxidation reduction : IEA
  • MF: GO:0050136 : NADH dehydrogenase (quinone) activity : IEA
  • MF: GO:0048038 : quinone binding : IEA
  • CC: GO:0016021 : integral to membrane : IEA
  • MF: GO:0016491 : oxidoreductase activity : IEA
  • MF: GO:0008137 : NADH dehydrogenase (ubiquinone) activity : IEA
Domain Structure from CDD
  • Oxidored_q4: NADH-ubiquinone/plastoquinone oxidoreductase, chain 3. NADH dehydrogenase subunit A; Validated

See domain structure on NCBI Conserved Domain Database
Domain structure from Pfam
See domain structure on Pfam Database
The table at right lists genes that may be "functionally linked to" (i.e., participate in a common biological process, or form a protein complex with) the subject gene of this page, as determined by two sequence-independent methods, including phylogenetic profiling and operon membership (determined by OperonDB). (Info.) These linkages may also be viewed graphically using the program VisANT, by clicking on the headers of the table. Note: VisANT requires Java. To install the latest version of Java, see
gene neighbourhoods
phylogenetic profile
HP1262NADH dehydrogenase subunit C
HP1258hypothetical protein
HP1259hypothetical protein
HP1261NADH dehydrogenase subunit B
HP1267NADH dehydrogenase subunit H  
HP1269NADH dehydrogenase subunit J  
HP1270NADH dehydrogenase subunit K  
HP1272NADH dehydrogenase subunit M  
HP1268NADH dehydrogenase subunit I  
HP1273NADH dehydrogenase subunit N  
HP1263NADH dehydrogenase subunit D  
Metabolic Annotation from Palsson Lab

Metabolic Reaction: NDH_1

NADH dehydrogenase (menaquinone) (complex I)
3 h[c] + mqn6[c] + nadph[c] -> 2 h[e] + mql6[c] + nadp[c]
Respiratory chain
Other Genes

Source: Ported to COMBREX by Segre's Lab