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Gene nth from Bacillus subtilis subsp. subtilis str. 168: endonuclease III
Member of NCBI Protein Clusters CLSK2518244(See COMBREX Page ) (See NCBI page)
NCBI Entrez GeneID 939036
UniProtKB accession
RefSeq Protein accession NP_390115.1 (PROVISIONAL)
Gene Symbol(s)
  • symbol: nth
  • locus tag: BSU22340
Organism Bacillus subtilis subsp. subtilis str. 168 (NCBI TaxID: 224308)
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Source Predicted function(s)
NCBI Protein Cluster Prediction endonuclease III
Source References Functional description
GSDB Under Review probable endonuclease III (source organism: Bacillus subtilis; strain specific ID: NCBI_TaxID=1423)
Functional Status greenGreen (experimental evidence, uncurated)
EC number
GO terms
  • MF: GO:0003824 : catalytic activity : IEA
  • MF: GO:0046872 : metal ion binding : IEA
  • CC: GO:0005622 : intracellular : IEA
  • BP: GO:0006281 : DNA repair : IEA
  • MF: GO:0003906 : DNA-(apurinic or apyrimidinic site) lyase activity : IEA
  • BP: GO:0006284 : base-excision repair : IEA
  • MF: GO:0051536 : iron-sulfur cluster binding : IEA
  • MF: GO:0016829 : lyase activity : IEA
  • MF: GO:0004519 : endonuclease activity : IEA
  • BP: GO:0006974 : response to DNA damage stimulus : IEA
  • BP: GO:0008152 : metabolic process : IEA
  • MF: GO:0016787 : hydrolase activity : IEA
  • MF: GO:0051539 : 4 iron, 4 sulfur cluster binding : IEA
  • MF: GO:0016798 : hydrolase activity, acting on glycosyl bonds : IEA
  • MF: GO:0003677 : DNA binding : IEA
Domain Structure from CDD
  • ENDO3c: endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alk.... (More)
  • Nth: Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]

See domain structure on NCBI Conserved Domain Database
Domain structure from Pfam
See domain structure on Pfam Database
Based on the function of this gene, COMBREX predictions were made to the following related genes (mouse over gene symbol for details) [Download ]
nth