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Gene yadB from Escherichia coli str. K-12 substr. MG1655: glutamyl-Q tRNA(Asp) synthetase
Member of NCBI Protein Clusters PRK05710(See COMBREX Page ) (See NCBI page)
NCBI Entrez GeneID 944846
UniProtKB accession
RefSeq Protein accession NP_414686.3 (PROVISIONAL)
Gene Symbol(s)
  • symbol: yadB
  • locus tag: b0144
  • aliases: ECK0143, JW5892
Organism Escherichia coli str. K-12 substr. MG1655 (NCBI TaxID: 511145)
Other Cross References:
  • S
    Structure(s) available in PDB: 1NZJ 4A91
  • C
    Gene cloned by a participant in the Protein Structure Initiative (PSI): TargetDB. (To obtain a clone, please contact the PSI:Biology-Materials Repository.)
  • U
    Protein purified by a participant in the Protein Structure Initiative (PSI): TargetDB. (If you are interested in collaborating to obtain the protein, please contact the Northeast Structural Genomics consortium).
  • Protein described in EcoCyc: EG11362
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Contribute a predicted function for this gene (free text, GO terms, or EC number) (info). Be sure to check the list of current predicted functions in the section immediately below beforehand.
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Source Predicted function(s)
NCBI Protein Cluster Prediction glutamyl-Q tRNA(Asp) synthetase
Source References Functional description
[PMID: 15150343]
[PMID: 15096594]
[PMID: 15096612]
[PMID: 15003446]
[PMID: 18602926]
Glutamyl-Q tRNA(Asp) synthetase (source organism: Escherichia coli (strain K12).; strain specific ID: )
Functional Status greenGreen (experimental evidence, uncurated)
EC number 6.1.1.- (See reaction via BRENDA)) (Source: NCBI RefSeq)
GO terms
  • BP: GO:0002097 : tRNA wobble base modification : IDA
  • MF: GO:0008270 : zinc ion binding : ISS
  • MF: GO:0046872 : metal ion binding : IEA
  • MF: GO:0005524 : ATP binding : IEA
  • MF: GO:0016874 : ligase activity : IEA
  • MF: GO:0008270 : zinc ion binding : IEA
  • BP: GO:0006418 : tRNA aminoacylation for protein translation : IEA
  • MF: GO:0005524 : ATP binding : IDA
  • MF: GO:0016876 : ligase activity, forming aminoacyl-tRNA and related compounds : IEA
  • MF: GO:0004812 : aminoacyl-tRNA ligase activity : IEA
  • CC: GO:0005737 : cytoplasm : IEA
  • MF: GO:0000166 : nucleotide binding : IEA
  • BP: GO:0006412 : translation : IEA
Domain Structure from CDD
  • nt_trans: nucleotidyl transferase superfamily. CTP:phosphocholine cytidylyltransferase (CCT) catalyzes the condensation of CTP and.... (More)
  • nt_trans: nucleotidyl transferase superfamily. nt_trans (nucleotidyl transferase) This superfamily includes the class I amino-acyl.... (More)

See domain structure on NCBI Conserved Domain Database
Domain structure from Pfam
See domain structure on Pfam Database
Based on the function of this gene, COMBREX predictions were made to the following related genes (mouse over gene symbol for details) [Download ]
EcolC_3515 , ECP_0154 , ECs0148 , ECSE_0144 , gluQ (5) , yadB (20)
The table at right lists genes that may be "functionally linked to" (i.e., participate in a common biological process, or form a protein complex with) the subject gene of this page, as determined by two sequence-independent methods, including phylogenetic profiling and operon membership (determined by OperonDB). (Info.) These linkages may also be viewed graphically using the program VisANT, by clicking on the headers of the table. Note: VisANT requires Java. To install the latest version of Java, see
 gene neighbourhoods
pcnBpoly(A) polymerase I
dksADNA-binding transcriptional regulator of rRNA tran