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Gene potF from Escherichia coli str. K-12 substr. MG1655: putrescine transporter subunit: periplasmic-binding component of ABC superfamily
Member of NCBI Protein Clusters PRK10682(See COMBREX Page ) (See NCBI page)
NCBI Entrez GeneID 945480
UniProtKB accession
RefSeq Protein accession NP_415375.1 (PROVISIONAL)
Gene Symbol(s)
  • symbol: potF
  • locus tag: b0854
  • aliases: ECK0845, JW0838
Organism Escherichia coli str. K-12 substr. MG1655 (NCBI TaxID: 511145)
Other Cross References:
  • S
    Structure(s) available in PDB: 1A99
  • C
    Gene cloned by a participant in the Protein Structure Initiative (PSI): TargetDB. (To obtain a clone, please contact the PSI:Biology-Materials Repository.)
  • U
    Protein purified by a participant in the Protein Structure Initiative (PSI): TargetDB. (If you are interested in collaborating to obtain the protein, please contact the Northeast Structural Genomics consortium).
  • Protein described in EcoCyc: EG11629
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Source Predicted function(s)
NCBI Protein Cluster Prediction putrescine transporter subunit: periplasmic-binding component of ABC superfamily
Source References Functional description
GSDB Under Review putrescine-binding periplasmic protein (source organism: Escherichia coli K12; strain specific ID: NCBI_TaxID=83333)
Functional Status greenGreen (experimental evidence, uncurated)
GO terms
  • BP: GO:0015847 : putrescine transport : IDA
  • MF: GO:0015594 : putrescine-importing ATPase activity : IMP
  • CC: GO:0030288 : outer membrane-bounded periplasmic space : IEA
  • MF: GO:0015594 : putrescine-importing ATPase activity : RCA
  • BP: GO:0006810 : transport : IEA
  • CC: GO:0043190 : ATP-binding cassette (ABC) transporter complex : RCA
  • CC: GO:0042597 : periplasmic space : IEA
  • MF: GO:0005215 : transporter activity : IEA
Domain Structure from CDD
  • PotD: Spermidine/putrescine-binding periplasmic protein [Amino acid transport and metabolism]

See domain structure on NCBI Conserved Domain Database
Domain structure from Pfam
See domain structure on Pfam Database
Based on the function of this gene, COMBREX predictions were made to the following related genes (mouse over gene symbol for details) [Download ]
CKO_02253 , EcolC_2742 , ECP_0868 , ECs0934 , ECSE_0912 , Ent638_1368 , ESA_02483 , potF (42) , SARI_02053 , SeAg_B0914 , SeD_A0982 , SeHA_C1011 , SeSA_A1030 , SG0925 , SNSL254_A0950 , SPAB_02612 , SSPA1755 , YPA_0621 , YPDSF_2366 , YPK_2730 , YPN_2649 , YPTS_1458
The table at right lists genes that may be "functionally linked to" (i.e., participate in a common biological process, or form a protein complex with) the subject gene of this page, as determined by two sequence-independent methods, including phylogenetic profiling and operon membership (determined by OperonDB). (Info.) These linkages may also be viewed graphically using the program VisANT, by clicking on the headers of the table. Note: VisANT requires Java. To install the latest version of Java, see
 gene neighbourhoods
phylogenetic profile
potGputrescine transporter subunit: ATP-binding compon
potIputrescine transporter subunit: membrane component 
ydcUpredicted spermidine/putrescine transporter subuni 
ydcVpredicted spermidine/putrescine transporter subuni 
ydcTpredicted spermidine/putrescine transporter subuni 
potCpolyamine transporter subunit 
potBpolyamine transporter subunit 
potHputrescine transporter subunit: membrane component 
afuCCP4-6 prophage; predicted ferric transporter subun 
potApolyamine transporter subunit 
Metabolic Annotation from Palsson Lab

Metabolic Reaction: PTRCabc

putrescine transport via ABC system
atp[c] + h2o[c] + ptrc[e] -> adp[c] + h[c] + pi[c] + ptrc[c]
Transport, Extracellular
Other Genes

Source: Ported to COMBREX by Segre's Lab