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Gene lnt from Escherichia coli str. K-12 substr. MG1655: apolipoprotein N-acyltransferase
Member of NCBI Protein Clusters PRK00302(See COMBREX Page ) (See NCBI page)
NCBI Entrez GeneID 946201
UniProtKB accession
RefSeq Protein accession NP_415190.1 (PROVISIONAL)
Gene Symbol(s)
  • symbol: lnt
  • locus tag: b0657
  • aliases: ECK0649, JW0654, cutE
Organism Escherichia coli str. K-12 substr. MG1655 (NCBI TaxID: 511145)
Other Cross References:
  • S
    Structure(s) available in PDB:
  • C
    Gene cloned by a participant in the Protein Structure Initiative (PSI): TargetDB. (To obtain a clone, please contact the PSI:Biology-Materials Repository.)
  • U
    Protein purified by a participant in the Protein Structure Initiative (PSI): TargetDB. (If you are interested in collaborating to obtain the protein, please contact the Northeast Structural Genomics consortium).
  • Protein described in EcoCyc: EG10168
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Post a comment about this gene to appear on this page (info).
Source Predicted function(s)
NCBI Protein Cluster Prediction apolipoprotein N-acyltransferase
Source References Functional description
[PMID: 2032623]
[PMID: 8344936]
[PMID: 15919996]
Apolipoprotein N-acyltransferase (source organism: Escherichia coli (strain K12).; strain specific ID: )
Functional Status greenGreen (experimental evidence, uncurated)
EC number 2.3.1.- (See reaction via BRENDA)) (Source: NCBI RefSeq)
GO terms
  • BP: GO:0042158 : lipoprotein biosynthetic process : IEA
  • MF: GO:0005507 : copper ion binding : IEA
  • CC: GO:0005886 : plasma membrane : IEA
  • CC: GO:0016021 : integral to membrane : IEA
  • BP: GO:0006807 : nitrogen compound metabolic process : IEA
  • MF: GO:0016410 : N-acyltransferase activity : IEA
  • MF: GO:0016740 : transferase activity : IEA
  • MF: GO:0016810 : hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds : IEA
  • MF: GO:0008415 : acyltransferase activity : IEA
  • CC: GO:0016020 : membrane : IEA
Domain Structure from CDD
  • lnt: apolipoprotein N-acyltransferase; Reviewed
  • ALP_N-acyl_transferase: Apolipoprotein N-acyl transferase (class 9 nitrilases). ALP N-acyl transferase (Lnt), is an essential membrane-bound enz.... (More)

See domain structure on NCBI Conserved Domain Database
Domain structure from Pfam
See domain structure on Pfam Database
Based on the function of this gene, COMBREX predictions were made to the following related genes (mouse over gene symbol for details) [Download ]
lnt (50)
The table at right lists genes that may be "functionally linked to" (i.e., participate in a common biological process, or form a protein complex with) the subject gene of this page, as determined by two sequence-independent methods, including phylogenetic profiling and operon membership (determined by OperonDB). (Info.) These linkages may also be viewed graphically using the program VisANT, by clicking on the headers of the table. Note: VisANT requires Java. To install the latest version of Java, see
 gene neighbourhoods
phylogenetic profile
domain fusion
ybeXpredicteed ion transport
rplY50S ribosomal subunit protein L25 
ruvCcomponent of RuvABC resolvasome, endonuclease 
arnCundecaprenyl phosphate-L-Ara4FN transferase  
Phenotype Description Expression
Candidate essential gene Identified as essential gene in one or more studies (see references) Knock out
PMID: 13129938
(not essential)
PMID: 17700540
(candidate essential)
PMID: 20029369
(candidate essential)