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Gene yciB from Escherichia coli str. K-12 substr. MG1655: predicted inner membrane protein
Member of NCBI Protein Clusters PRK00259(See COMBREX Page ) (See NCBI page)
NCBI Entrez GeneID 946228
UniProtKB accession
RefSeq Protein accession NP_415770.1 (PROVISIONAL)
Gene Symbol(s)
  • symbol: yciB
  • locus tag: b1254
  • aliases: ECK1248, JW1246, ispA
Organism Escherichia coli str. K-12 substr. MG1655 (NCBI TaxID: 511145)
Other Cross References:
  • S
    Structure(s) available in PDB:
  • C
    Gene cloned by a participant in the Protein Structure Initiative (PSI): TargetDB. (To obtain a clone, please contact the PSI:Biology-Materials Repository.)
  • U
    Protein purified by a participant in the Protein Structure Initiative (PSI): TargetDB. (If you are interested in collaborating to obtain the protein, please contact the Northeast Structural Genomics consortium).
  • Protein described in EcoCyc: EG11122
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Contribute a predicted function for this gene (free text, GO terms, or EC number) (info). Be sure to check the list of current predicted functions in the section immediately below beforehand.
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Post a comment about this gene to appear on this page (info).
Source Predicted function(s)
NCBI Protein Cluster Prediction intracellular septation protein A
Functional Status blueblue (function predicted, no experimental evidence)
Source of prediction NCBI Protein Clusters info
BLASTP hits to experimentally validated proteins This gene does not have a BLAST match to any experimentally validated gene with an E value below 1e-5
GO terms
  • CC: GO:0016020 : membrane : IEA
  • BP: GO:0051301 : cell division : IEA
  • BP: GO:0007049 : cell cycle : IEA
  • BP: GO:0000917 : barrier septum formation : IEA
  • CC: GO:0005886 : plasma membrane : IEA
  • CC: GO:0016021 : integral to membrane : IEA
Domain Structure from CDD
  • IspA: Intracellular septation protein A. intracellular septation protein A; Reviewed

See domain structure on NCBI Conserved Domain Database
Domain structure from Pfam
See domain structure on Pfam Database
The table at right lists genes that may be "functionally linked to" (i.e., participate in a common biological process, or form a protein complex with) the subject gene of this page, as determined by two sequence-independent methods, including phylogenetic profiling and operon membership (determined by OperonDB). (Info.) These linkages may also be viewed graphically using the program VisANT, by clicking on the headers of the table. Note: VisANT requires Java. To install the latest version of Java, see www.java.com
 gene neighbourhoods
phylogenetic profile
dxs1-deoxyxylulose-5-phosphate synthase, thiamine-req
 
 
yciAAcyl-CoA esterase, role unknown
 
 
xseBexonuclease VII small subunit
 
 
nthDNA glycosylase and apyrimidinic (AP) lyase (endon 
 
ispUundecaprenyl pyrophosphate synthase 
 
bamElipoprotein component of BamABCDE OM biogenesis co 
 
secBprotein export chaperone 
 
holCDNA polymerase III, chi subunit