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Gene cysP from Escherichia coli str. K-12 substr. MG1655: thiosulfate transporter subunit
Member of NCBI Protein Clusters PRK10852(See COMBREX Page ) (See NCBI page)
NCBI Entrez GeneID 946883
UniProtKB accession
RefSeq Protein accession NP_416920.1 (PROVISIONAL)
Gene Symbol(s)
  • symbol: cysP
  • locus tag: b2425
  • aliases: ECK2420, JW2418
Organism Escherichia coli str. K-12 substr. MG1655 (NCBI TaxID: 511145)
Other Cross References:
  • S
    Structure(s) available in PDB:
  • C
    Gene cloned by a participant in the Protein Structure Initiative (PSI): TargetDB. (To obtain a clone, please contact the PSI:Biology-Materials Repository.)
  • U
    Protein purified by a participant in the Protein Structure Initiative (PSI): TargetDB. (If you are interested in collaborating to obtain the protein, please contact the Northeast Structural Genomics consortium).
  • Protein described in EcoCyc: EG10195
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Source Predicted function(s)
NCBI Protein Cluster Prediction thiosulfate transporter subunit
Source References Functional description
GSDB Under Review cysP ABC superfamily (peri_bind) thiosulfate transport protein (source organism: Escherichia coli K12; strain specific ID: NCBI_TaxID=83333)
Functional Status greenGreen (experimental evidence, uncurated)
GO terms
  • CC: GO:0030288 : outer membrane-bounded periplasmic space : IEA
  • BP: GO:0006810 : transport : IEA
  • BP: GO:0008272 : sulfate transport : IEA
  • MF: GO:0015419 : sulfate transmembrane-transporting ATPase activity : IEA
  • MF: GO:0005515 : protein binding : IPI
  • CC: GO:0042597 : periplasmic space : IEA
  • MF: GO:0005215 : transporter activity : IEA
  • MF: GO:0008271 : secondary active sulfate transmembrane transporter activity : IEA
Domain structure from Pfam
See domain structure on Pfam Database
Based on the function of this gene, COMBREX predictions were made to the following related genes (mouse over gene symbol for details) [Download ]
CKO_00365 , cysP (41) , EcolC_1254 , ECP_2448 , ECs3296 , ECSE_2715 , Ent638_2951 , ESA_00822 , SARI_00444 , SPAB_00510 , SSPA0396
The table at right lists genes that may be "functionally linked to" (i.e., participate in a common biological process, or form a protein complex with) the subject gene of this page, as determined by two sequence-independent methods, including phylogenetic profiling and operon membership (determined by OperonDB). (Info.) These linkages may also be viewed graphically using the program VisANT, by clicking on the headers of the table. Note: VisANT requires Java. To install the latest version of Java, see
 gene neighbourhoods
cysUsulfate/thiosulfate transporter subunit
Metabolic Annotation from Palsson Lab

Metabolic Reaction: SULabc

sulfate transport via ABC system
atp[c] + h2o[c] + so4[e] -> adp[c] + h[c] + pi[c] + so4[c]
Transport, Extracellular
Other Genes

Metabolic Reaction: TSULabc

thiosulfate transport via ABC system
atp[c] + h2o[c] + tsul[e] -> adp[c] + h[c] + pi[c] + tsul[c]
Transport, Extracellular
Other Genes

Source: Ported to COMBREX by Segre's Lab