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Gene rpsP from Escherichia coli str. K-12 substr. MG1655: 30S ribosomal subunit protein S16
Member of NCBI Protein Clusters PRK00040(See COMBREX Page ) (See NCBI page)
NCBI Entrez GeneID 947103
UniProtKB accession
RefSeq Protein accession NP_417100.1 (PROVISIONAL)
Gene Symbol(s)
  • symbol: rpsP
  • locus tag: b2609
  • aliases: ECK2606, JW2590
Organism Escherichia coli str. K-12 substr. MG1655 (NCBI TaxID: 511145)
Other Cross References:
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Source Predicted function(s)
NCBI Protein Cluster Prediction 30S ribosomal protein S16
Source References Functional description
[PMID: 336510]
[PMID: 8730873]
[PMID: 9298646]
[PMID: 10094780]
[PMID: 12809609]
[PMID: 16272117]
30S ribosomal protein S16 (source organism: Escherichia coli (strain K12).; strain specific ID: K)
Functional Status greenGreen (experimental evidence, uncurated)
GO terms
  • BP: GO:0000028 : ribosomal small subunit assembly : IDA
  • MF: GO:0004520 : endodeoxyribonuclease activity : IDA
  • CC: GO:0005622 : intracellular : IEA
  • MF: GO:0003735 : structural constituent of ribosome : IEA
  • CC: GO:0005840 : ribosome : IEA
  • MF: GO:0004518 : nuclease activity : IEA
  • MF: GO:0003735 : structural constituent of ribosome : IDA
  • CC: GO:0030529 : ribonucleoprotein complex : IEA
  • BP: GO:0006412 : translation : IEA
  • CC: GO:0022627 : cytosolic small ribosomal subunit : IDA
  • MF: GO:0004519 : endonuclease activity : IEA
  • MF: GO:0016787 : hydrolase activity : IEA
  • MF: GO:0043566 : structure-specific DNA binding : IDA
Domain Structure from CDD
  • Ribosomal_S16: Ribosomal protein S16. 30S ribosomal protein S16; Provisional

See domain structure on NCBI Conserved Domain Database
Domain structure from Pfam
See domain structure on Pfam Database
Based on the function of this gene, COMBREX predictions were made to the following related genes (mouse over gene symbol for details) [Download ]
NT01EI_3223 , rpsP (52)
The table at right lists genes that may be "functionally linked to" (i.e., participate in a common biological process, or form a protein complex with) the subject gene of this page, as determined by two sequence-independent methods, including phylogenetic profiling and operon membership (determined by OperonDB). (Info.) These linkages may also be viewed graphically using the program VisANT, by clicking on the headers of the table. Note: VisANT requires Java. To install the latest version of Java, see
 phylogenetic profile
gene neighbourhoods
rplS50S ribosomal subunit protein L19
ffhSignal Recognition Particle (SRP) component with 4 
rluApseudouridine synthase for 23S rRNA (position 746)
rpmI50S ribosomal subunit protein L35
rplQ50S ribosomal subunit protein L17
frrribosome recycling factor
truCtRNA U65 pseudouridine synthase
rpsR30S ribosomal subunit protein S18
rluC23S rRNA pseudouridine synthase; specific to U955,
obgEGTPase involved in cell partioning and DNA repair
rplL50S ribosomal subunit protein L7/L12
rpsF30S ribosomal subunit protein S6
mnmAtRNA (5-methylaminomethyl-2-thiouridylate)-methylt
fmt10-formyltetrahydrofolate:L-methionyl-tRNA(fMet) N
rpmG50S ribosomal subunit protein L33
ftsHprotease, ATP-dependent zinc-metallo
pthpeptidyl-tRNA hydrolase
aspSaspartyl-tRNA synthetase
ssbsingle-stranded DNA-binding protein
rncRNase III
rpmA50S ribosomal subunit protein L27
tsfprotein chain elongation factor EF-Ts
lepAback-translocating Elongation Factor EF4, GTPase
arnAfused UDP-L-Ara4N formyltransferase/UDP-GlcA C-4'-
acpPacyl carrier protein (ACP)
rluD23S rRNA pseudouridine synthase; specific to U1911
yidCmembrane protein insertase
tufAprotein chain elongation factor EF-Tu (duplicate o
tufBprotein chain elongation factor EF-Tu (duplicate o
rplI50S ribosomal subunit protein L9
prfApeptide chain release factor RF-1
Phenotype Description Expression
Candidate essential gene Identified as essential gene in one or more studies (see references) Knock out
PMID: 13129938
(candidate essential)
PMID: 17700540
(candidate essential)
PMID: 20029369
(candidate essential)