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Gene cbpA from Escherichia coli str. K-12 substr. MG1655: curved DNA-binding protein, DnaJ homologue that functions as a co-chaperone of DnaK
Member of NCBI Protein Clusters PRK10266(See COMBREX Page ) (See NCBI page)
NCBI Entrez GeneID 947572
UniProtKB accession
RefSeq Protein accession NP_415520.1 (PROVISIONAL)
Gene Symbol(s)
  • symbol: cbpA
  • locus tag: b1000
  • aliases: ECK0991, JW0985
Organism Escherichia coli str. K-12 substr. MG1655 (NCBI TaxID: 511145)
Other Cross References:
  • S
    Structure(s) available in PDB: 2KQX
  • C
    Gene cloned by a participant in the Protein Structure Initiative (PSI): TargetDB. (To obtain a clone, please contact the PSI:Biology-Materials Repository.)
  • U
    Protein purified by a participant in the Protein Structure Initiative (PSI): TargetDB. (If you are interested in collaborating to obtain the protein, please contact the Northeast Structural Genomics consortium).
  • Protein described in EcoCyc: EG12193
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Source Predicted function(s)
NCBI Protein Cluster Prediction curved DNA-binding protein CbpA
Source References Functional description
[PMID: 8302830]
[PMID: 7997164]
[PMID: 10947847]
[PMID: 15184371]
Curved DNA-binding protein (source organism: Escherichia coli (strain K12).; strain specific ID: K12)
Functional Status greenGreen (experimental evidence, uncurated)
GO terms
  • MF: GO:0031072 : heat shock protein binding : IEA
  • CC: GO:0005737 : cytoplasm : IEA
  • CC: GO:0009295 : nucleoid : IEA
  • CC: GO:0005737 : cytoplasm : IDA
  • BP: GO:0006457 : protein folding : IEA
  • MF: GO:0051082 : unfolded protein binding : IEA
  • MF: GO:0003677 : DNA binding : IEA
  • MF: GO:0003681 : bent DNA binding : IEA
Domain Structure from CDD
  • PRK10266: curved DNA-binding protein CbpA; Provisional
  • DnaJ_C: DnaJ C terminal region. This family consists of the C terminal region form the DnaJ protein. Although the function of th.... (More)
  • DnaJ: DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in pro.... (More)

See domain structure on NCBI Conserved Domain Database
Domain structure from Pfam
See domain structure on Pfam Database
Based on the function of this gene, COMBREX predictions were made to the following related genes (mouse over gene symbol for details) [Download ]
cbpA (36) , CKO_02066 , EcolC_2595 , ECP_1000 , ECs1155 , ECSE_1062 , SARI_01889 , SeAg_B1071 , SeD_A1187 , SeHA_C1222 , SeSA_A1176 , SNSL254_A1207 , SPAB_02438 , SSPA1615