Combrex Enter Keyword, gene symbol, or identifier (more options; Help )
Enter species name
Gene functional status (select)
Phenotype association (select)[View list of phenotypes]
Check to restrict search to:
Genes in Category A-C and Emerging/Re-Emerging pathogens
Genes in curated Protein Clusters
Genes with predictions submitted to COMBREX
P
Genes with solved structures in PDB
S
Genes with Pfam domains shared with human proteins
H
Genes with products purified by PSI
U
Genes cloned by PSI
C
close options

 

Gene rplP from Escherichia coli str. K-12 substr. MG1655: 50S ribosomal subunit protein L16
Member of NCBI Protein Clusters PRK09203(See COMBREX Page ) (See NCBI page)
NCBI Entrez GeneID 947806
UniProtKB accession
RefSeq Protein accession NP_417772.1 (PROVISIONAL)
Gene Symbol(s)
  • symbol: rplP
  • locus tag: b3313
  • aliases: ECK3300, JW3275
Organism Escherichia coli str. K-12 substr. MG1655 (NCBI TaxID: 511145)
Other Cross References:
Initiate the grant application process for experimentally validating this gene (Important notice about COMBREX grants.)
Contribute a predicted function for this gene (free text, GO terms, or EC number) (info). Be sure to check the list of current predicted functions in the section immediately below beforehand.
Nominate this gene for the Gold Standard Gene Database (if you believe it has been experimentally validated) (info).
Post a comment about this gene to appear on this page (info).
Source Predicted function(s)
NCBI Protein Cluster Prediction 50S ribosomal protein L16
Source References Functional description
GSDB
[PMID: 786730]
[PMID: 3298242]
[PMID: 10094780]
[PMID: 12809609]
[PMID: 16272117]
50S ribosomal protein L16 (source organism: Escherichia coli (strain K12).; strain specific ID: K)
Functional Status greenGreen (experimental evidence, uncurated)
GO terms
  • CC: GO:0030529 : ribonucleoprotein complex : IEA
  • CC: GO:0005622 : intracellular : IEA
  • BP: GO:0006412 : translation : IEA
  • MF: GO:0000049 : tRNA binding : IEA
  • MF: GO:0019843 : rRNA binding : IEA
  • MF: GO:0003723 : RNA binding : IEA
  • MF: GO:0003735 : structural constituent of ribosome : IEA
  • CC: GO:0005840 : ribosome : IEA
Domain Structure from CDD
  • Ribosomal_L16_L10e: Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplas.... (More)

See domain structure on NCBI Conserved Domain Database
Domain structure from Pfam
See domain structure on Pfam Database
Based on the function of this gene, COMBREX predictions were made to the following related genes (mouse over gene symbol for details) [Download ]
NT01EI_3587 , rplP (132) , Tola_0106 , VCD_001774
The table at right lists genes that may be "functionally linked to" (i.e., participate in a common biological process, or form a protein complex with) the subject gene of this page, as determined by two sequence-independent methods, including phylogenetic profiling and operon membership (determined by OperonDB). (Info.) These linkages may also be viewed graphically using the program VisANT, by clicking on the headers of the table. Note: VisANT requires Java. To install the latest version of Java, see www.java.com
 gene neighbourhoods
rpsQ30S ribosomal subunit protein S17
 
rpmC50S ribosomal subunit protein L29
 
rpsC30S ribosomal subunit protein S3
 
Phenotype Description Expression
Class
Reference(s)
Candidate essential gene Identified as essential gene in one or more studies (see references) Knock out
PMID: 13129938
(not essential)
PMID: 17700540
(candidate essential)
PMID: 20029369
(candidate essential)