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Gene ugpC from Escherichia coli str. K-12 substr. MG1655: glycerol-3-phosphate transporter subunit
Member of NCBI Protein Clusters PRK11650(See COMBREX Page ) (See NCBI page)
NCBI Entrez GeneID 947953
UniProtKB accession
RefSeq Protein accession NP_417907.2 (PROVISIONAL)
Gene Symbol(s)
  • symbol: ugpC
  • locus tag: b3450
  • aliases: ECK3434, JW3415
Organism Escherichia coli str. K-12 substr. MG1655 (NCBI TaxID: 511145)
Other Cross References:
  • S
    Structure(s) available in PDB:
  • C
    Gene cloned by a participant in the Protein Structure Initiative (PSI): TargetDB. (To obtain a clone, please contact the PSI:Biology-Materials Repository.)
  • U
    Protein purified by a participant in the Protein Structure Initiative (PSI): TargetDB. (If you are interested in collaborating to obtain the protein, please contact the Northeast Structural Genomics consortium).
  • Protein described in EcoCyc: EG11048
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Contribute a predicted function for this gene (free text, GO terms, or EC number) (info). Be sure to check the list of current predicted functions in the section immediately below beforehand.
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Post a comment about this gene to appear on this page (info).
Source Predicted function(s)
NCBI Protein Cluster Prediction glycerol-3-phosphate transporter ATP-binding subunit
Source References Functional description
[PMID: 363686]
[PMID: 7042685]
[PMID: 2842304]
[PMID: 1987150]
[PMID: 8407831]
[PMID: 8282692]
sn-glycerol-3-phosphate import ATP-binding protein UgpC (source organism: Escherichia coli (strain K12).; strain specific ID: K12)
Functional Status greenGreen (experimental evidence, uncurated)
EC number (See reaction via BRENDA)) (Source: BRENDA)
GO terms
  • BP: GO:0008643 : carbohydrate transport : IEA
  • MF: GO:0015430 : glycerol-3-phosphate-transporting ATPase activity : ISS
  • CC: GO:0005886 : plasma membrane : IEA
  • CC: GO:0043190 : ATP-binding cassette (ABC) transporter complex : IEA
  • BP: GO:0070811 : glycerol-2-phosphate transport : IMP
  • MF: GO:0017111 : nucleoside-triphosphatase activity : IEA
  • MF: GO:0015430 : glycerol-3-phosphate-transporting ATPase activity : IEA
  • MF: GO:0016887 : ATPase activity : IEA
  • CC: GO:0016020 : membrane : IEA
  • CC: GO:0019898 : extrinsic to membrane : IEA
  • MF: GO:0005215 : transporter activity : IEA
  • MF: GO:0000166 : nucleotide binding : IEA
  • BP: GO:0015794 : glycerol-3-phosphate transport : IMP
  • BP: GO:0015794 : glycerol-3-phosphate transport : IEA
  • MF: GO:0016787 : hydrolase activity : IEA
  • BP: GO:0006810 : transport : IEA
  • MF: GO:0016820 : hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances : IEA
  • MF: GO:0005524 : ATP binding : IEA
Domain Structure from CDD
  • ABC_MalK_N: The N-terminal ATPase domain of the maltose transporter, MalK. ATP binding cassette (ABC) proteins function from bacter.... (More)
  • ugpC: glycerol-3-phosphate transporter ATP-binding subunit; Provisional
  • TOBE_2: TOBE domain. This model describes a multigene family of molybdenum-pterin binding proteins of about 70 amino acids in Cl.... (More)

See domain structure on NCBI Conserved Domain Database
Domain structure from Pfam
See domain structure on Pfam Database
Based on the function of this gene, COMBREX predictions were made to the following related genes (mouse over gene symbol for details) [Download ]
ugpC (47)
The table at right lists genes that may be "functionally linked to" (i.e., participate in a common biological process, or form a protein complex with) the subject gene of this page, as determined by two sequence-independent methods, including phylogenetic profiling and operon membership (determined by OperonDB). (Info.) These linkages may also be viewed graphically using the program VisANT, by clicking on the headers of the table. Note: VisANT requires Java. To install the latest version of Java, see
 gene neighbourhoods
domain fusion
ugpEglycerol-3-phosphate transporter subunit
ybhRpredicted transporter subunit: membrane component  
ybhSpredicted transporter subunit: membrane component  
yhhJPredicted permease subunit, ABC transporter superf 
Metabolic Annotation from Palsson Lab

Metabolic Reaction: GLYC3Pabc

sn-Glycerol 3-phosphate transport via ABC system
atp[c] + glyc3p[e] + h2o[c] -> adp[c] + glyc3p[c] + h[c] + pi[c]
Transport, Extracellular
Other Genes

Source: Ported to COMBREX by Segre's Lab