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Gene ugpA from Escherichia coli str. K-12 substr. MG1655: glycerol-3-phosphate transporter subunit
Member of NCBI Protein Clusters PRK10561(See COMBREX Page ) (See NCBI page)
NCBI Entrez GeneID 947957
UniProtKB accession
RefSeq Protein accession NP_417909.1 (PROVISIONAL)
Gene Symbol(s)
  • symbol: ugpA
  • locus tag: b3452
  • aliases: ECK3436, JW3417, psiB, psiC
Organism Escherichia coli str. K-12 substr. MG1655 (NCBI TaxID: 511145)
Other Cross References:
  • S
    Structure(s) available in PDB:
  • C
    Gene cloned by a participant in the Protein Structure Initiative (PSI): TargetDB. (To obtain a clone, please contact the PSI:Biology-Materials Repository.)
  • U
    Protein purified by a participant in the Protein Structure Initiative (PSI): TargetDB. (If you are interested in collaborating to obtain the protein, please contact the Northeast Structural Genomics consortium).
  • Protein described in EcoCyc: EG11046
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Source Predicted function(s)
NCBI Protein Cluster Prediction glycerol-3-phosphate transporter permease
Source References Functional description
GSDB Under Review sn-glycerol-3-phosphate transport system permease protein ugpA (source organism: Escherichia coli K12; strain specific ID: NCBI_TaxID=83333)
Functional Status greenGreen (experimental evidence, uncurated)
EC number (See reaction via BRENDA)) (Source: BRENDA)
GO terms
  • MF: GO:0005215 : transporter activity : IEA
  • CC: GO:0016020 : membrane : IEA
  • BP: GO:0015794 : glycerol-3-phosphate transport : IMP
  • BP: GO:0006810 : transport : IEA
  • CC: GO:0005886 : plasma membrane : IEA
  • CC: GO:0016021 : integral to membrane : IEA
  • BP: GO:0070811 : glycerol-2-phosphate transport : IMP
Domain Structure from CDD
  • TM_PBP2: Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters .... (More)
  • LplB: ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]

See domain structure on NCBI Conserved Domain Database
Domain structure from Pfam
See domain structure on Pfam Database
Based on the function of this gene, COMBREX predictions were made to the following related genes (mouse over gene symbol for details) [Download ]
CKO_04873 , EcolC_0264 , ECP_3545 , ECs4298 , ECSE_3718 , Ent638_3855 , ESA_04291 , SARI_04077 , SPAB_04418 , Spro_0235 , SSPA3181 , ugpA (41)
The table at right lists genes that may be "functionally linked to" (i.e., participate in a common biological process, or form a protein complex with) the subject gene of this page, as determined by two sequence-independent methods, including phylogenetic profiling and operon membership (determined by OperonDB). (Info.) These linkages may also be viewed graphically using the program VisANT, by clicking on the headers of the table. Note: VisANT requires Java. To install the latest version of Java, see
 gene neighbourhoods
phylogenetic profile
ugpBglycerol-3-phosphate transporter subunit
ugpEglycerol-3-phosphate transporter subunit
ycjNpredicted sugar transporter subunit: periplasmic-b 
ycjPpredicted sugar transporter subunit: membrane comp 
Metabolic Annotation from Palsson Lab

Metabolic Reaction: GLYC3Pabc

sn-Glycerol 3-phosphate transport via ABC system
atp[c] + glyc3p[e] + h2o[c] -> adp[c] + glyc3p[c] + h[c] + pi[c]
Transport, Extracellular
Other Genes

Source: Ported to COMBREX by Segre's Lab