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Gene ugpE from Escherichia coli str. K-12 substr. MG1655: glycerol-3-phosphate transporter subunit
Member of NCBI Protein Clusters PRK10973(See COMBREX Page ) (See NCBI page)
NCBI Entrez GeneID 947959
UniProtKB accession
RefSeq Protein accession NP_417908.1 (PROVISIONAL)
Gene Symbol(s)
  • symbol: ugpE
  • locus tag: b3451
  • aliases: ECK3435, JW3416
Organism Escherichia coli str. K-12 substr. MG1655 (NCBI TaxID: 511145)
Other Cross References:
  • S
    Structure(s) available in PDB:
  • C
    Gene cloned by a participant in the Protein Structure Initiative (PSI): TargetDB. (To obtain a clone, please contact the PSI:Biology-Materials Repository.)
  • U
    Protein purified by a participant in the Protein Structure Initiative (PSI): TargetDB. (If you are interested in collaborating to obtain the protein, please contact the Northeast Structural Genomics consortium).
  • Protein described in EcoCyc: EG11049
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Post a comment about this gene to appear on this page (info).
Source Predicted function(s)
NCBI Protein Cluster Prediction glycerol-3-phosphate transporter membrane protein
Functional Status blueblue (function predicted, no experimental evidence)
Source of prediction NCBI Protein Clusters info
EC number (See reaction via BRENDA)) (Source: BRENDA)
BLASTP hits to experimentally validated proteins
green yesQ from Bacillus subtilis subsp. subtilis str. 168
(%_identity=28.15; E_val=2e-23; BitScore=104.0)

other hits with E-value < 1e-05
Share the same Pfam domain composition with the following experimentally validated proteins
green yecS from Escherichia coli str. K-12 substr. MG1655

to see the rest 81 genes click here
GO terms
  • MF: GO:0005215 : transporter activity : IEA
  • CC: GO:0016020 : membrane : IEA
  • BP: GO:0015794 : glycerol-3-phosphate transport : IMP
  • BP: GO:0006810 : transport : IEA
  • CC: GO:0005886 : plasma membrane : IEA
  • CC: GO:0016021 : integral to membrane : IEA
  • BP: GO:0070811 : glycerol-2-phosphate transport : IMP
Domain Structure from CDD
  • TM_PBP2: Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters .... (More)

See domain structure on NCBI Conserved Domain Database
Domain structure from Pfam
See domain structure on Pfam Database
The table at right lists genes that may be "functionally linked to" (i.e., participate in a common biological process, or form a protein complex with) the subject gene of this page, as determined by two sequence-independent methods, including phylogenetic profiling and operon membership (determined by OperonDB). (Info.) These linkages may also be viewed graphically using the program VisANT, by clicking on the headers of the table. Note: VisANT requires Java. To install the latest version of Java, see
 gene neighbourhoods
phylogenetic profile
ugpCglycerol-3-phosphate transporter subunit
ugpAglycerol-3-phosphate transporter subunit
malFmaltose transporter subunit 
ycjNpredicted sugar transporter subunit: periplasmic-b 
ugpBglycerol-3-phosphate transporter subunit 
ycjOpredicted sugar transporter subunit: membrane comp 
Metabolic Annotation from Palsson Lab

Metabolic Reaction: GLYC3Pabc

sn-Glycerol 3-phosphate transport via ABC system
atp[c] + glyc3p[e] + h2o[c] -> adp[c] + glyc3p[c] + h[c] + pi[c]
Transport, Extracellular
Other Genes

Source: Ported to COMBREX by Segre's Lab