Combrex Enter Keyword, gene symbol, or identifier (more options; Help )
Enter species name
Gene functional status (select)
Phenotype association (select)[View list of phenotypes]
Check to restrict search to:
Genes in Category A-C and Emerging/Re-Emerging pathogens
Genes in curated Protein Clusters
Genes with predictions submitted to COMBREX
Genes with solved structures in PDB
Genes with Pfam domains shared with human proteins
Genes with products purified by PSI
Genes cloned by PSI
close options


Gene sbp from Escherichia coli str. K-12 substr. MG1655: sulfate transporter subunit
Member of NCBI Protein Clusters PRK10752(See COMBREX Page ) (See NCBI page)
NCBI Entrez GeneID 948411
UniProtKB accession
RefSeq Protein accession NP_418352.1 (PROVISIONAL)
Gene Symbol(s)
  • symbol: sbp
  • locus tag: b3917
  • aliases: ECK3909, JW3888
Organism Escherichia coli str. K-12 substr. MG1655 (NCBI TaxID: 511145)
Other Cross References:
  • S
    Structure(s) available in PDB:
  • C
    Gene cloned by a participant in the Protein Structure Initiative (PSI): TargetDB. (To obtain a clone, please contact the PSI:Biology-Materials Repository.)
  • U
    Protein purified by a participant in the Protein Structure Initiative (PSI): TargetDB. (If you are interested in collaborating to obtain the protein, please contact the Northeast Structural Genomics consortium).
  • Protein described in EcoCyc: EG10929
Initiate the grant application process for experimentally validating this gene (Important notice about COMBREX grants.)
Contribute a predicted function for this gene (free text, GO terms, or EC number) (info). Be sure to check the list of current predicted functions in the section immediately below beforehand.
Nominate this gene for the Gold Standard Gene Database (if you believe it has been experimentally validated) (info).
Post a comment about this gene to appear on this page (info).
Source Predicted function(s)
NCBI Protein Cluster Prediction sulfate transporter subunit
COMBREX sbp sulfate-binding protein (source organism: Salmonella enterica subsp. enterica serovar Typhimurium; strain specific ID: NCBI_TaxID=90371) [More information on this prediction]
Source References Functional description
GSDB Under Review sulfate-binding protein (source organism: Escherichia coli K12; strain specific ID: NCBI_TaxID=83333)
Functional Status greenGreen (experimental evidence, uncurated)
GO terms
  • MF: GO:0005215 : transporter activity : IEA
  • MF: GO:0008271 : secondary active sulfate transmembrane transporter activity : IEA
  • CC: GO:0030288 : outer membrane-bounded periplasmic space : IEA
  • BP: GO:0006810 : transport : IEA
  • BP: GO:0008272 : sulfate transport : IEA
  • MF: GO:0015419 : sulfate transmembrane-transporting ATPase activity : IEA
  • CC: GO:0042597 : periplasmic space : IEA
Domain structure from Pfam
See domain structure on Pfam Database
Based on the function of this gene, COMBREX predictions were made to the following related genes (mouse over gene symbol for details) [Download ]
CKO_03083 , EcolC_4101 , ECP_4126 , ECs4842 , ECSE_4206 , Ent638_4055 , ESA_04128 , SARI_03580 , sbp (39) , sbp1 (3) , SeAg_B4309 , SeD_A4461 , SeHA_C4394 , SeSA_A4280 , SG2177 , SNSL254_A4392 , SPAB_05036 , Spro_4806 , SSPA3634 , YPA_3462 , YpAngola_A0089 , YPDSF_3825 , YPK_4125 , YPN_3769 , YpsIP31758_0090 , YPTS_0078
The table at right lists genes that may be "functionally linked to" (i.e., participate in a common biological process, or form a protein complex with) the subject gene of this page, as determined by two sequence-independent methods, including phylogenetic profiling and operon membership (determined by OperonDB). (Info.) These linkages may also be viewed graphically using the program VisANT, by clicking on the headers of the table. Note: VisANT requires Java. To install the latest version of Java, see
 phylogenetic profile
bfrbacterioferritin, iron storage and detoxification
Metabolic Annotation from Palsson Lab

Metabolic Reaction: SULabc

sulfate transport via ABC system
atp[c] + h2o[c] + so4[e] -> adp[c] + h[c] + pi[c] + so4[c]
Transport, Extracellular
Other Genes

Metabolic Reaction: TSULabc

thiosulfate transport via ABC system
atp[c] + h2o[c] + tsul[e] -> adp[c] + h[c] + pi[c] + tsul[c]
Transport, Extracellular
Other Genes

Source: Ported to COMBREX by Segre's Lab