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Gene malE from Escherichia coli str. K-12 substr. MG1655: maltose transporter subunit
Member of NCBI Protein Clusters PRK09474(See COMBREX Page ) (See NCBI page)
NCBI Entrez GeneID 948538
UniProtKB accession
RefSeq Protein accession NP_418458.1 (PROVISIONAL)
Gene Symbol(s)
  • symbol: malE
  • locus tag: b4034
  • aliases: ECK4026, JW3994, malJ
Organism Escherichia coli str. K-12 substr. MG1655 (NCBI TaxID: 511145)
Other Cross References:
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Source Predicted function(s)
NCBI Protein Cluster Prediction maltose ABC transporter periplasmic protein
Source References Functional description
GSDB
[PMID: 6088507]
[PMID: 9298646]
[PMID: 9600841]
[PMID: 2002054]
[PMID: 1420181]
[PMID: 9309217]
Maltose-binding periplasmic protein (source organism: Escherichia coli (strain K12).; strain specific ID: K12)
Functional Status greenGreen (experimental evidence, uncurated)
GO terms
  • BP: GO:0008643 : carbohydrate transport : IEA
  • MF: GO:0005215 : transporter activity : IGI
  • CC: GO:0055052 : ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing : IGI
  • MF: GO:0015423 : maltose-transporting ATPase activity : IDA
  • MF: GO:0015609 : maltooligosaccharide-importing ATPase activity : IMP
  • BP: GO:0042956 : maltodextrin transport : IMP
  • BP: GO:0006810 : transport : IGI
  • BP: GO:0015768 : maltose transport : IGI
  • MF: GO:0005363 : maltose transmembrane transporter activity : IEA
  • CC: GO:0042597 : periplasmic space : IEA
  • MF: GO:0005215 : transporter activity : IEA
  • MF: GO:0048030 : disaccharide binding : IPI
  • CC: GO:0042597 : periplasmic space : IDA
  • BP: GO:0008643 : carbohydrate transport : IGI
  • BP: GO:0006810 : transport : IEA
  • BP: GO:0015768 : maltose transport : IEA
  • CC: GO:0043190 : ATP-binding cassette (ABC) transporter complex : IGI
  • BP: GO:0015768 : maltose transport : IDA
Domain Structure from CDD
  • MalE: Maltose-binding periplasmic proteins/domains [Carbohydrate transport and metabolism]

See domain structure on NCBI Conserved Domain Database
Domain structure from Pfam
See domain structure on Pfam Database
Based on the function of this gene, COMBREX predictions were made to the following related genes (mouse over gene symbol for details) [Download ]
malE (60) , NT01EI_0216
The table at right lists genes that may be "functionally linked to" (i.e., participate in a common biological process, or form a protein complex with) the subject gene of this page, as determined by two sequence-independent methods, including phylogenetic profiling and operon membership (determined by OperonDB). (Info.) These linkages may also be viewed graphically using the program VisANT, by clicking on the headers of the table. Note: VisANT requires Java. To install the latest version of Java, see www.java.com
 gene neighbourhoods
domain fusion
malFmaltose transporter subunit
 
 
lacZbeta-D-galactosidase 
 
Metabolic Annotation from Palsson Lab

Metabolic Reaction: MALTHXabc

Name
maltohexaose transport via ABC system
Formula
atp[c] + h2o[c] + malthx[e] -> adp[c] + h[c] + malthx[c] + pi[c]
Pathway
Transport, Extracellular
Other Genes

Metabolic Reaction: MALTPTabc

Name
maltopentaose transport via ABC system
Formula
atp[c] + h2o[c] + maltpt[e] -> adp[c] + h[c] + maltpt[c] + pi[c]
Pathway
Transport, Extracellular
Other Genes

Metabolic Reaction: MALTTRabc

Name
Maltotriose transport via ABC system
Formula
atp[c] + h2o[c] + malttr[e] -> adp[c] + h[c] + malttr[c] + pi[c]
Pathway
Transport, Extracellular
Other Genes

Metabolic Reaction: MALTTTRabc

Name
maltotetraose transport via ABC system
Formula
atp[c] + h2o[c] + maltttr[e] -> adp[c] + h[c] + maltttr[c] + pi[c]
Pathway
Transport, Extracellular
Other Genes

Metabolic Reaction: MALTabc

Name
maltose transport via ABC system
Formula
atp[c] + h2o[c] + malt[e] -> adp[c] + h[c] + malt[c] + pi[c]
Pathway
Transport, Extracellular
Other Genes

Source: Ported to COMBREX by Segre's Lab
KEGG