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Phenotypes
Summary
Phenotype Description #Genes Functional status Source
Antibiotic resistance class Aac2I Aminoglycoside N-acetyltransferase, which modifies aminoglycosides by acetylation. 3 0 0 3 0 ARDB
Antibiotic resistance class Aac2Ic Aminoglycoside N-acetyltransferase, which modifies aminoglycosides by acetylation. 9 0 0 9 0 ARDB
Antibiotic resistance class Aac2Id Aminoglycoside N-acetyltransferase, which modifies aminoglycosides by acetylation. 1 0 0 1 0 ARDB
Antibiotic resistance class Aac3Ia Aminoglycoside N-acetyltransferase, which modifies aminoglycosides by acetylation. 4 0 0 4 0 ARDB
Antibiotic resistance class Aac3IIa Aminoglycoside N-acetyltransferase, which modifies aminoglycosides by acetylation. 5 0 0 5 0 ARDB
Antibiotic resistance class Aac3VI Aminoglycoside N-acetyltransferase, which modifies aminoglycosides by acetylation. 4 0 0 4 0 ARDB
Antibiotic resistance class Aac6Ib Aminoglycoside N-acetyltransferase, which modifies aminoglycosides by acetylation. 15 0 0 15 0 ARDB
Antibiotic resistance class Aac6Ie Aminoglycoside N-acetyltransferase, which modifies aminoglycosides by acetylation. 12 0 0 12 0 ARDB
Antibiotic resistance class aad9Ib Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation. 19 0 0 19 0 ARDB
Antibiotic resistance class AadD Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation. 8 0 1 7 0 ARDB
Antibiotic resistance class AcrA Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. 49 0 1 48 0 ARDB
Antibiotic resistance class AcrB Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. 84 0 1 83 0 ARDB
Antibiotic resistance class AdeA Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. 4 0 0 4 0 ARDB
Antibiotic resistance class AdeB Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. 5 0 0 5 0 ARDB
Antibiotic resistance class AdeC Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. 4 0 0 4 0 ARDB
Antibiotic resistance class AmrA Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. 10 0 0 10 0 ARDB
Antibiotic resistance class AmrB Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. 17 0 0 17 0 ARDB
Antibiotic resistance class Ant2Ia Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation. 3 0 0 3 0 ARDB
Antibiotic resistance class Ant3Ia Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation. 27 0 0 27 0 ARDB
Antibiotic resistance class Ant6Ia Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation. 1 0 0 1 0 ARDB
Antibiotic resistance class Aph33Ia Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation. 1 0 0 1 0 ARDB
Antibiotic resistance class Aph33Ib Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation. 55 0 0 55 0 ARDB
Antibiotic resistance class Aph3Ia Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation. 29 0 0 29 0 ARDB
Antibiotic resistance class Aph3Ib Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation. 2 0 0 2 0 ARDB
Antibiotic resistance class Aph3Ic Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation. 1 0 0 1 0 ARDB
Antibiotic resistance class Aph3IIIa Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation. 5 0 1 4 0 ARDB
Antibiotic resistance class Aph6Ia Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation. 1 0 0 1 0 ARDB
Antibiotic resistance class Aph6Ic Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation. 3 0 0 3 0 ARDB
Antibiotic resistance class Aph6Id Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation. 49 0 0 49 0 ARDB
Antibiotic resistance class arnA Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides. 27 0 1 26 0 ARDB
Antibiotic resistance class BacA Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate. 354 0 1 353 0 ARDB
Antibiotic resistance class bcr 49 0 1 48 0 ARDB
Antibiotic resistance class BcrA ABC transporter system, bacitracin efflux pump. 2 0 0 2 0 ARDB
Antibiotic resistance class BL1_ceps Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properties. 1 0 0 1 0 ARDB
Antibiotic resistance class BL1_cmy2 Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properties. 13 0 0 13 0 ARDB
Antibiotic resistance class BL1_ec Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properties. 31 0 1 30 0 ARDB
Antibiotic resistance class BL1_fox Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properties. 1 0 0 1 0 ARDB
Antibiotic resistance class BL1_mox Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properties. 1 0 0 1 0 ARDB
Antibiotic resistance class BL1_och Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properties. 1 0 0 1 0 ARDB
Antibiotic resistance class BL1_pao Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properties. 4 0 0 4 0 ARDB
Antibiotic resistance class BL1_pse Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properties. 1 0 0 1 0 ARDB
Antibiotic resistance class BL1_sm Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properties. 2 0 0 2 0 ARDB
Antibiotic resistance class BL2_kpc Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properties. 4 0 0 4 0 ARDB
Antibiotic resistance class BL2_len Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properties. 2 0 0 2 0 ARDB
Antibiotic resistance class BL2_veb Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properties. 1 0 0 1 0 ARDB
Antibiotic resistance class BL2a_1 Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properties. 17 0 0 17 0 ARDB
Antibiotic resistance class BL2a_III Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properties. 17 0 1 16 0 ARDB
Antibiotic resistance class BL2a_III2 Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properties. 2 0 0 2 0 ARDB
Antibiotic resistance class BL2a_pc Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properties. 15 0 0 15 0 ARDB
Antibiotic resistance class BL2b_rob Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properties. 6 0 0 6 0 ARDB
Antibiotic resistance class BL2b_tem Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properties. 5 0 0 5 0 ARDB
Antibiotic resistance class BL2b_tem1 Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properties. 34 0 0 34 0 ARDB
Antibiotic resistance class BL2b_tem2 Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properties. 3 0 0 3 0 ARDB
Antibiotic resistance class BL2be_ctxm Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properties. 7 0 0 7 0 ARDB
Antibiotic resistance class BL2be_shv2 Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properties. 8 0 0 8 0 ARDB
Antibiotic resistance class BL2c_pse1 Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properties. 1 0 0 1 0 ARDB
Antibiotic resistance class BL2d_lcr1 Class D beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properties. 1 0 0 1 0 ARDB
Antibiotic resistance class BL2d_oxa1 Class D beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properties. 1 0 1 0 0 ARDB
Antibiotic resistance class BL2d_oxa2 Class D beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properties. 5 0 0 5 0 ARDB
Antibiotic resistance class BL2d_oxa9 Class D beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properties. 4 0 0 4 0 ARDB
Antibiotic resistance class BL2e_cepa Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properties. 2 0 0 2 0 ARDB
Antibiotic resistance class BL2e_y56 Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properties. 1 0 0 1 0 ARDB
Antibiotic resistance class BL3_cphA Class B beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properties. 2 0 0 2 0 ARDB
Antibiotic resistance class BL3_imp Class B beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properties. 2 0 0 2 0 ARDB
Antibiotic resistance class BL3_l Class B beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properties. 2 0 0 2 0 ARDB
Antibiotic resistance class BL3_shw Class B beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properties. 1 0 0 1 0 ARDB
Antibiotic resistance class Ble Binding protein with a strong affinity to the bleomycin family of antibiotics, which confers resistance to these antibiotics by preventing the bleomycin-induced DNA breakage 8 0 0 8 0 ARDB
Antibiotic resistance class Blt Major facilitator superfamily transporter. Multidrug resistance efflux pump. 1 0 1 0 0 ARDB
Antibiotic resistance class Bmr Major facilitator superfamily transporter. Multidrug resistance efflux pump. 1 0 1 0 0 ARDB
Antibiotic resistance class catA1 Group A chloramphenicol acetyltransferase, which can inactivate chloramphenicol. 14 0 0 14 0 ARDB
Antibiotic resistance class catA13 Group A chloramphenicol acetyltransferase, which can inactivate chloramphenicol. 1 0 0 1 0 ARDB
Antibiotic resistance class catA15 Group A chloramphenicol acetyltransferase, which can inactivate chloramphenicol. 1 0 0 1 0 ARDB
Antibiotic resistance class catA2 Group A chloramphenicol acetyltransferase, which can inactivate chloramphenicol. 10 0 0 10 0 ARDB
Antibiotic resistance class catA3 Group A chloramphenicol acetyltransferase, which can inactivate chloramphenicol. 5 0 0 5 0 ARDB
Antibiotic resistance class catA4 Group A chloramphenicol acetyltransferase, which can inactivate chloramphenicol. 1 0 0 1 0 ARDB
Antibiotic resistance class catA7 Group A chloramphenicol acetyltransferase, which can inactivate chloramphenicol. 6 0 0 6 0 ARDB
Antibiotic resistance class catA8 Group A chloramphenicol acetyltransferase, which can inactivate chloramphenicol. 3 0 0 3 0 ARDB
Antibiotic resistance class catA9 Group A chloramphenicol acetyltransferase, which can inactivate chloramphenicol. 7 0 0 7 0 ARDB
Antibiotic resistance class catB1 Group B chloramphenicol acetyltransferase, which can inactivate chloramphenicol. Also referred to as xenobiotic acetyltransferase. 1 0 0 1 0 ARDB
Antibiotic resistance class catB2 Group B chloramphenicol acetyltransferase, which can inactivate chloramphenicol. Also referred to as xenobiotic acetyltransferase. 2 0 0 2 0 ARDB
Antibiotic resistance class catB3 Group B chloramphenicol acetyltransferase, which can inactivate chloramphenicol. Also referred to as xenobiotic acetyltransferase. 3 0 0 3 0 ARDB
Antibiotic resistance class catB4 Group B chloramphenicol acetyltransferase, which can inactivate chloramphenicol. Also referred to as xenobiotic acetyltransferase. 2 0 1 1 0 ARDB
Antibiotic resistance class catB5 Group B chloramphenicol acetyltransferase, which can inactivate chloramphenicol. Also referred to as xenobiotic acetyltransferase. 2 0 0 2 0 ARDB
Antibiotic resistance class CeoA Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. 18 0 2 16 0 ARDB
Antibiotic resistance class CeoB Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. 30 0 2 28 0 ARDB
Antibiotic resistance class cml_e1 Major facilitator superfamily transporter, chloramphenicol efflux pump. 5 0 0 5 0 ARDB
Antibiotic resistance class cml_e3 Major facilitator superfamily transporter, chloramphenicol efflux pump. 11 0 0 11 0 ARDB
Antibiotic resistance class cml_e5 Major facilitator superfamily transporter, chloramphenicol efflux pump. 1 0 0 1 0 ARDB
Antibiotic resistance class cml_e8 Major facilitator superfamily transporter, chloramphenicol efflux pump. 7 0 0 7 0 ARDB
Antibiotic resistance class dfrA1 Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim. 9 0 0 9 0 ARDB
Antibiotic resistance class dfrA12 Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim. 6 0 0 6 0 ARDB
Antibiotic resistance class dfrA14 Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim. 4 0 0 4 0 ARDB
Antibiotic resistance class dfrA17 Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim. 1 0 0 1 0 ARDB
Antibiotic resistance class dfrA19 Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim. 2 0 0 2 0 ARDB
Antibiotic resistance class EmeA Major facilitator superfamily transporter. Multidrug resistance efflux pump. 4 0 0 4 0 ARDB
Antibiotic resistance class emrd Multidrug resistance efflux pump. 50 0 1 49 0 ARDB
Antibiotic resistance class EmrE Multidrug resistance efflux pump. 23 0 1 22 0 ARDB
Antibiotic resistance class ErmA rRNA adenine N-6-methyltransferase, which can methylate adenine at position 2058 of 23S rRNA, conferring resistance to erythromycin. 19 0 0 19 0 ARDB
Antibiotic resistance class ErmB rRNA adenine N-6-methyltransferase, which can methylate adenine at position 2058 of 23S rRNA, conferring resistance to erythromycin. 19 0 0 19 0 ARDB
Antibiotic resistance class ErmC rRNA adenine N-6-methyltransferase, which can methylate adenine at position 2058 of 23S rRNA, conferring resistance to erythromycin. 13 0 0 12 1 ARDB
Antibiotic resistance class ErmE rRNA adenine N-6-methyltransferase, which can methylate adenine at position 2058 of 23S rRNA, conferring resistance to erythromycin. 1 0 0 1 0 ARDB
Antibiotic resistance class ErmO rRNA adenine N-6-methyltransferase, which can methylate adenine at position 2058 of 23S rRNA, conferring resistance to erythromycin. 1 0 0 1 0 ARDB
Antibiotic resistance class ErmT rRNA adenine N-6-methyltransferase, which can methylate adenine at position 2058 of 23S rRNA, conferring resistance to erythromycin. 2 0 0 2 0 ARDB
Antibiotic resistance class ErmX rRNA adenine N-6-methyltransferase, which can methylate adenine at position 2058 of 23S rRNA, conferring resistance to erythromycin. 5 0 0 5 0 ARDB
Antibiotic resistance class FosB Glutathione transferase, metalloglutathione transferase which confers resistance to fosfomycin by catalyzing the addition of glutathione to fosfomycin 45 1 0 44 0 ARDB
Antibiotic resistance class FosX Glutathione transferase, metalloglutathione transferase which confers resistance to fosfomycin by catalyzing the addition of glutathione to fosfomycin 6 0 1 5 0 ARDB
Antibiotic resistance class fusB Involved in the resistance (detoxification) of the fungal toxin fusaric acid. 1 0 0 1 0 ARDB
Antibiotic resistance class fusH Esterase enzyme inactivating fusidic acid 1 0 0 1 0 ARDB
Antibiotic resistance class KsgA Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance. 58 0 1 57 0 ARDB
Antibiotic resistance class LmrB ABC transporter system, Macrolide-Lincosamide-Streptogramin B efflux pump. 2 0 1 1 0 ARDB
Antibiotic resistance class lmrp 2 0 0 2 0 ARDB
Antibiotic resistance class LnuA Lincosamide nucleotidyltransferase. 13 0 0 13 0 ARDB
Antibiotic resistance class lsa ABC efflux family that is resistant to MLS antibiotics 1 0 0 1 0 ARDB
Antibiotic resistance class MacA Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system. 50 0 1 49 0 ARDB
Antibiotic resistance class MacB Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system. 49 0 1 48 0 ARDB
Antibiotic resistance class mdfa 49 0 1 48 0 ARDB
Antibiotic resistance class mdr 3 0 1 2 0 ARDB
Antibiotic resistance class mdtE Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. 27 0 1 26 0 ARDB
Antibiotic resistance class mdtF Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. 28 0 1 27 0 ARDB
Antibiotic resistance class mdtG Major facilitator superfamily transporter. Multidrug resistance efflux pump. 46 0 0 46 0 ARDB
Antibiotic resistance class MdtH Major facilitator superfamily transporter. Multidrug resistance efflux pump. 51 0 1 50 0 ARDB
Antibiotic resistance class MdtK Major facilitator superfamily transporter. Multidrug resistance efflux pump. 51 0 1 50 0 ARDB
Antibiotic resistance class MdtL Major facilitator superfamily transporter. Multidrug resistance efflux pump. 31 0 1 30 0 ARDB
Antibiotic resistance class MdtM Major facilitator superfamily transporter. Multidrug resistance efflux pump. 33 0 1 32 0 ARDB
Antibiotic resistance class MdtN Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. 29 0 0 29 0 ARDB
Antibiotic resistance class MdtO Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. 27 0 0 27 0 ARDB
Antibiotic resistance class MdtP Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. 28 0 1 27 0 ARDB
Antibiotic resistance class mecA Penicillin binding protein, which has a low affinity for beta-lactams and catalyze a penicillin-insensitive transpeptidation. 12 0 0 12 0 ARDB
Antibiotic resistance class MecR1 Methicillin-resistance regulatory protein for mecA 11 0 0 11 0 ARDB
Antibiotic resistance class MefA Major facilitator superfamily transporter, Macrolide-Lincosamide-Streptogramin B efflux pump. 4 0 0 4 0 ARDB
Antibiotic resistance class MepA Multi antimicrobial extrusion (MATE) efflux family protein. Multidrug resistance efflux pump. 17 0 1 16 0 ARDB
Antibiotic resistance class MexA Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. 4 0 1 3 0 ARDB
Antibiotic resistance class MexB Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. 6 0 1 5 0 ARDB
Antibiotic resistance class MexC Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. 1 0 0 1 0 ARDB
Antibiotic resistance class MexD Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. 9 0 0 9 0 ARDB
Antibiotic resistance class MexE Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. 4 0 0 4 0 ARDB
Antibiotic resistance class MexF Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. 16 0 0 16 0 ARDB
Antibiotic resistance class mexh Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. 4 0 0 4 0 ARDB
Antibiotic resistance class mexi Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. 4 0 0 4 0 ARDB
Antibiotic resistance class mexw Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. 13 0 0 13 0 ARDB
Antibiotic resistance class MexX Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. 4 0 0 4 0 ARDB
Antibiotic resistance class MexY Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. 4 0 0 4 0 ARDB
Antibiotic resistance class MfpA Pentapeptide repeat family, which protects DNA gyrase from the inhibition of quinolones. 9 0 0 9 0 ARDB
Antibiotic resistance class MphA Macrolide phosphotransferase 6 0 0 6 0 ARDB
Antibiotic resistance class MphC Macrolide phosphotransferase 2 0 0 2 0 ARDB
Antibiotic resistance class MsrA ABC transporter system, Macrolide-Lincosamide-Streptogramin B efflux pump. 2 0 0 2 0 ARDB
Antibiotic resistance class nora 19 0 0 19 0 ARDB
Antibiotic resistance class norM Multi antimicrobial extrusion (MATE) efflux family protein. Multidrug resistance efflux pump. 4 0 1 3 0 ARDB
Antibiotic resistance class OpcM Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. 10 0 0 10 0 ARDB
Antibiotic resistance class opmd Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. 4 0 0 4 0 ARDB
Antibiotic resistance class OprA Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. 6 0 0 6 0 ARDB
Antibiotic resistance class OprJ Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. 4 0 0 4 0 ARDB
Antibiotic resistance class OprM Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. 4 0 1 3 0 ARDB
Antibiotic resistance class OprN Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. 4 0 0 4 0 ARDB
Antibiotic resistance class pbp1a The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) 4 0 1 3 0 ARDB
Antibiotic resistance class pbp1b The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) 2 0 0 2 0 ARDB
Antibiotic resistance class pbp2 The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) 15 0 0 15 0 ARDB
Antibiotic resistance class pbp2b The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) 6 0 0 6 0 ARDB
Antibiotic resistance class pbp2x The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) 11 0 2 9 0 ARDB
Antibiotic resistance class PmrA Major facilitator superfamily transporter. Multidrug resistance efflux pump. 11 0 0 11 0 ARDB
Antibiotic resistance class Qac Small Multidrug Resistance (SMR) protein family. Multidrug resistance efflux pump, which consists of two proteins. 1 0 0 1 0 ARDB
Antibiotic resistance class QacA Multidrug efflux pump from bacterial pathogen staphylococcus aureus. Including QacA and QacB, both of which confer resistance to various toxic organic cations but differ in that QacB mediates lower levels of resistance to divalent cations. They differed by seven nucleotide subsititutions. 2 0 0 2 0 ARDB
Antibiotic resistance class QnrA Pentapeptide repeat family, which protects DNA gyrase from the inhibition of quinolones. 1 0 0 1 0 ARDB
Antibiotic resistance class QnrB Pentapeptide repeat family, which protects DNA gyrase from the inhibition of quinolones. 2 0 0 2 0 ARDB
Antibiotic resistance class QnrS Pentapeptide repeat family, which protects DNA gyrase from the inhibition of quinolones. 5 0 0 5 0 ARDB
Antibiotic resistance class RosA Efflux pump/potassium antiporter system. RosA: Major facilitator superfamily transporter. RosB: Potassium antiporter. 11 0 0 11 0 ARDB
Antibiotic resistance class RosB Efflux pump/potassium antiporter system. RosA: Major facilitator superfamily transporter. RosB: Potassium antiporter. 13 0 0 13 0 ARDB
Antibiotic resistance class SmeA Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. 2 0 0 2 0 ARDB
Antibiotic resistance class SmeB Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. 2 0 0 2 0 ARDB
Antibiotic resistance class SmeC Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. 2 0 0 2 0 ARDB
Antibiotic resistance class SmeD Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. 2 0 0 2 0 ARDB
Antibiotic resistance class SmeE Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. 2 0 0 2 0 ARDB
Antibiotic resistance class SmeF Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. 2 0 0 2 0 ARDB
Antibiotic resistance class str Streptomycin resistance protein. 1 0 0 1 0 ARDB
Antibiotic resistance class Sul1 Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide. 55 0 0 55 0 ARDB
Antibiotic resistance class Sul2 Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide. 54 0 0 54 0 ARDB
Antibiotic resistance class Sul3 Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide. 3 0 0 3 0 ARDB
Antibiotic resistance class tcmA Major facilitator superfamily transporter. Resistance to tetracenomycin C by an active tetracenomycin C efflux system which is probably energized by transmembrane electrochemical gradients. 3 0 0 3 0 ARDB
Antibiotic resistance class tet Ribosomal protection protein, which protects ribosome from the translation inhibition of tetracycline. 1 0 0 1 0 ARDB
Antibiotic resistance class tet33 Major facilitator superfamily transporter, tetracycline efflux pump. 3 0 0 3 0 ARDB
Antibiotic resistance class tet34 Xanthine-guanine phosphoribosyltransferase. Mechanism detail unknown. 5 0 0 5 0 ARDB
Antibiotic resistance class tet38 Major facilitator superfamily transporter, tetracycline efflux pump. 14 0 0 14 0 ARDB
Antibiotic resistance class tetA Major facilitator superfamily transporter, tetracycline efflux pump. 30 0 0 30 0 ARDB
Antibiotic resistance class tetB Major facilitator superfamily transporter, tetracycline efflux pump. 20 0 1 19 0 ARDB
Antibiotic resistance class tetC Major facilitator superfamily transporter, tetracycline efflux pump. 10 0 0 10 0 ARDB
Antibiotic resistance class tetD Major facilitator superfamily transporter, tetracycline efflux pump. 7 0 0 7 0 ARDB
Antibiotic resistance class tetG Major facilitator superfamily transporter, tetracycline efflux pump. 2 0 0 2 0 ARDB
Antibiotic resistance class tetH Major facilitator superfamily transporter, tetracycline efflux pump. 3 0 0 3 0 ARDB
Antibiotic resistance class tetJ Major facilitator superfamily transporter, tetracycline efflux pump. 1 0 0 1 0 ARDB
Antibiotic resistance class tetK Major facilitator superfamily transporter, tetracycline efflux pump. 10 0 0 10 0 ARDB
Antibiotic resistance class tetL Major facilitator superfamily transporter, tetracycline efflux pump. 8 0 1 7 0 ARDB
Antibiotic resistance class tetM Ribosomal protection protein, which protects ribosome from the translation inhibition of tetracycline. 14 0 0 14 0 ARDB
Antibiotic resistance class tetO Ribosomal protection protein, which protects ribosome from the translation inhibition of tetracycline. 6 0 0 6 0 ARDB
Antibiotic resistance class tetPA Major facilitator superfamily transporter, tetracycline efflux pump. 2 0 0 2 0 ARDB
Antibiotic resistance class tetPB Ribosomal protection protein, which protects ribosome from the translation inhibition of tetracycline. 2 0 1 1 0 ARDB
Antibiotic resistance class tetS Ribosomal protection protein, which protects ribosome from the translation inhibition of tetracycline. 2 0 0 2 0 ARDB
Antibiotic resistance class tetV Major facilitator superfamily transporter, tetracycline efflux pump. 1 0 0 1 0 ARDB
Antibiotic resistance class tetW Ribosomal protection protein, which protects ribosome from the translation inhibition of tetracycline. 2 0 0 2 0 ARDB
Antibiotic resistance class tetZ Major facilitator superfamily transporter, tetracycline efflux pump. 1 0 0 1 0 ARDB
Antibiotic resistance class TmrB Mechanism unknown. 1 0 1 0 0 ARDB
Antibiotic resistance class TolC Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. 52 0 1 51 0 ARDB
Antibiotic resistance class VanA VanA type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate. 5 0 0 5 0 ARDB
Antibiotic resistance class VanB VanB type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate. 2 0 1 1 0 ARDB
Antibiotic resistance class VanHA VanA type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate. 5 0 0 5 0 ARDB
Antibiotic resistance class VanHB VanB type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate. 2 0 1 1 0 ARDB
Antibiotic resistance class VanRA VanA type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate. 7 0 0 7 0 ARDB
Antibiotic resistance class VanRB VanB type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate. 3 0 0 3 0 ARDB
Antibiotic resistance class VanSA VanA type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate. 7 0 0 7 0 ARDB
Antibiotic resistance class VanSB VanB type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate. 2 0 0 2 0 ARDB
Antibiotic resistance class VanWB VanB type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate. 2 0 0 2 0 ARDB
Antibiotic resistance class VanXA VanA type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate. 5 0 0 5 0 ARDB
Antibiotic resistance class VanXB VanB type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate. 2 0 0 2 0 ARDB
Antibiotic resistance class VanYA VanA type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate. 5 0 0 5 0 ARDB
Antibiotic resistance class VanYB VanB type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate. 2 0 0 2 0 ARDB
Antibiotic resistance class VanZ VanZ confers low-level VanZ confers low-level resistance to the glycopeptide antibiotic teicoplanin. 5 0 0 5 0 ARDB
Antibiotic resistance class VatB Virginiamycin A acetyltransferase, which can inactivate the target drug. 5 0 0 5 0 ARDB
Antibiotic resistance class VgaA ABC transporter system, Macrolide-Lincosamide-Streptogramin B efflux pump. 1 0 0 1 0 ARDB
Antibiotic resistance class VgbA Streptogramin B Lyase, which can deactivate the target drug by hydrolysis. 1 0 0 0 1 ARDB
Antibiotic resistance class YkkC Small Multidrug Resistance (SMR) protein family. Multidrug resistance efflux pump, which consists of two proteins. 2 0 1 1 0 ARDB
Antibiotic resistance class YkkD Small Multidrug Resistance (SMR) protein family. Multidrug resistance efflux pump, which consists of two proteins. 2 0 1 1 0 ARDB
Ciprofloxacin sensitivity Knockout confers increased sensitivity to ciprofloxacin 55 0 37 18 0 Prof. Jeffrey Miller
Enoxacin sensitivity Knockout confers increased sensitivity to enoxacin 47 0 31 16 0 Prof. Jeffrey Miller
Nitrofurantoin sensitivity Knockout confers increased sensitivity to nitrofurantoin 136 1 92 43 0 Prof. Jeffrey Miller
Metronidazole sensitivity Knockout confers increased sensitivity to metronidazole 82 0 63 19 0 Prof. Jeffrey Miller
Sulfamethoxazole sensitivity Knockout confers increased sensitivity to sulfamethoxazole 65 1 47 17 0 Prof. Jeffrey Miller
Rifampicin sensitivity Knockout confers increased sensitivity to rifampicin 87 2 64 21 0 Prof. Jeffrey Miller
Gentamicin sensitivity Knockout confers increased sensitivity to gentamicin 51 1 36 14 0 Prof. Jeffrey Miller
Tobramycin sensitivity Knockout confers increased sensitivity to tobramycin 60 1 43 16 0 Prof. Jeffrey Miller
Neomycin sensitivity Knockout confers increased sensitivity to neomycin 67 1 47 19 0 Prof. Jeffrey Miller
Streptomycin sensitivity Knockout confers increased sensitivity to streptomycin 29 1 22 6 0 Prof. Jeffrey Miller
Spectinomycin sensitivity Knockout confers increased sensitivity to spectinomycin 36 1 30 5 0 Prof. Jeffrey Miller
Tetracycline sensitivity Knockout confers increased sensitivity to tetracycline 56 0 37 19 0 Prof. Jeffrey Miller
Vancomycin sensitivity Knockout confers increased sensitivity to vancomycin 56 0 39 17 0 Prof. Jeffrey Miller
Ampicillin sensitivity Knockout confers increased sensitivity to ampicillin 85 1 54 30 0 Prof. Jeffrey Miller
Cephradine sensitivity Knockout confers increased sensitivity to cephradine 70 1 48 21 0 Prof. Jeffrey Miller
Cefoxitin sensitivity Knockout confers increased sensitivity to cefoxitin 56 1 35 20 0 Prof. Jeffrey Miller
Azetreonam sensitivity Knockout confers increased sensitivity to azetreonam 41 1 23 17 0 Prof. Jeffrey Miller
Colistin sensitivity Knockout confers increased sensitivity to colistin 52 1 36 15 0 Prof. Jeffrey Miller
Chloramphenicol sensitivity Knockout confers increased sensitivity to chloramphenicol 46 1 31 14 0 Prof. Jeffrey Miller
Erythromycin sensitivity Knockout confers increased sensitivity to erythromycin 52 1 39 12 0 Prof. Jeffrey Miller
Fusidic Acid sensitivity Knockout confers increased sensitivity to fusidic 43 0 33 10 0 Prof. Jeffrey Miller
Triclosan sensitivity Knockout confers increased sensitivity to triclosan 75 1 53 21 0 Prof. Jeffrey Miller
Candidate essential gene Identified as essential gene in one or more studies (see references) 2467 13 623 1675 156